PMID- 15678469
OWN - NLM
STAT- MEDLINE
DCOM- 20050630
LR  - 20101118
IS  - 1522-1946 (Print)
IS  - 1522-1946 (Linking)
VI  - 64
IP  - 2
DP  - 2005 Feb
TI  - Comparison of the left ventricular electromechanical map before percutaneous 
      coronary stent revascularization and at one-month follow-up in patients with a 
      recent ST elevation infarction.
PG  - 153-9
AB  - The study aimed to evaluate the safety and potential of percutaneous transluminal 
      electromechanical mapping (NOGA) in patients with regional myocardial wall 
      dysfunction after a recent ST elevation myocardial infarction (STEMI). Regional 
      myocardial wall dysfunction is a major cause of morbidity in survivors of ST 
      elevation myocardial infarction. Fifteen males who recently had suffered a STEMI 
      were studied prospectively with coronary angiography, ventriculography, and NOGA 
      before and 1 month after percutaneous coronary intervention (PCI). The left 
      ventricular angiographic ejection fraction increased from 50% +/- 11% before PCI 
      to 56% +/- 10% at follow-up (P = 0.006). Qualitative analysis of the NOGA color 
      map identified and outlined an area of regional wall dysfunction in all patients. 
      Quantitative analysis of the NOGA maps showed improvements at follow-up after PCI 
      in regional wall parameters of the infarct area (bipolar voltage: 1.7 +/- 1.4 mV 
      before intervention, 2.2 +/- 1.6 mV at follow-up, P = 0.05; local shortening, a 
      NOGA parameter on wall motion: 3.5% +/- 6.2% before, 7.4% +/- 5.8% at follow-up, 
      P = 0.01), whereas there were no changes in the noninfarcted area (bipolar 
      voltage: 2.7 +/- 2.5 mV before intervention, 2.8 +/- 2.6 mV at follow-up, P = 
      0.99; local shortening: 7.8% +/- 7.8% before, 8.2% +/- 7.8% at follow-up, P = 
      0.99). There were no complications to the NOGA procedures. In patients treated 
      with PCI for a recent STEMI, NOGA might be considered used in the quantification 
      of myocardial recovery and in the outlining of myocardial areas of incomplete or 
      no recovery.
CI  - 2005 Wiley-Liss, Inc.
FAU - Jorgensen, Erik
AU  - Jorgensen E
AD  - Cardiac Catheterization Laboratory, The Heart Center, Rigshospitalet, Copenhagen, 
      Denmark. erijk@rh.dk
FAU - Madsen, Theis
AU  - Madsen T
FAU - Kastrup, Jens
AU  - Kastrup J
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
MH  - Adult
MH  - Aged
MH  - Angioplasty, Balloon, Coronary
MH  - Body Surface Potential Mapping/*methods
MH  - Coronary Angiography
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*physiopathology/therapy
MH  - Prospective Studies
MH  - Statistics, Nonparametric
MH  - *Stents
MH  - Ventricular Dysfunction, Left/*physiopathology/therapy
EDAT- 2005/01/29 09:00
MHDA- 2005/07/01 09:00
CRDT- 2005/01/29 09:00
PHST- 2005/01/29 09:00 [pubmed]
PHST- 2005/07/01 09:00 [medline]
PHST- 2005/01/29 09:00 [entrez]
AID - 10.1002/ccd.20244 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2005 Feb;64(2):153-9. doi: 10.1002/ccd.20244.