PMID- 15690444 OWN - NLM STAT- MEDLINE DCOM- 20050329 LR - 20161124 IS - 0091-2751 (Print) IS - 0091-2751 (Linking) VI - 33 IP - 1 DP - 2005 Jan TI - Hemodynamics of the posterior cerebral arteries in neonates with periventricular leukomalacia. PG - 24-8 AB - PURPOSE: The purpose of this study was to evaluate the cerebral blood flow of the posterior cerebral arteries (PCAs) in neonates in relation to the onset of periventricular leukomalacia (PVL). METHODS: Among 57 low-birth-weight neonates studied, 7 were diagnosed with PVL with cyst formation on sonography and MRI. The mean cerebral blood flow velocity (CBFV) was measured in all the neonates by Doppler sonography through the posterior fontanel separately in the right and left PCA at days 0, 1, 2, 3, 4, 5, 7, 10, 14, 21, 28, 42, 56, and 70 following birth. RESULTS: In the 7 neonates with PVL the mean CBFV in the right PCA was significantly lower than that in neonates without PVL at days 10, 14, 21, 28, 42, 56, and 70; the mean CBFV in the left PCA of neonates with PVL was significantly lower than that in those without PVL at days 7, 10, 14, 21, 28, 42, 56, and 70. CBFV measured in neonates without PVL exhibited a gradual increase postnatally. In contrast, CBFV values for neonates with PVL plateaued after day 5 or 7. CONCLUSIONS: The serial measurement of PCA CBFV postnatally may prove useful as a predictor of the development of PVL. CI - 2004 Wiley Periodicals, Inc. FAU - Fukuda, Sumio AU - Fukuda S AD - Department of Pediatrics, Neonatology and Congenital Disorders, Graduate School of Medical Sciences, Nagoya City University, Kawasumi, Mizuho, Nagoya, Aichi 467-8601, Japan. FAU - Kuwabara, Satomi AU - Kuwabara S FAU - Yasuda, Mari AU - Yasuda M FAU - Mizuno, Keisuke AU - Mizuno K FAU - Kato, Takenori AU - Kato T FAU - Sugiura, Takahiro AU - Sugiura T FAU - Hussein, Mohamed Hamed AU - Hussein MH FAU - Kato, Ineko AU - Kato I FAU - Fujimoto, Shinji AU - Fujimoto S FAU - Sobajima, Hisanori AU - Sobajima H FAU - Togari, Hajime AU - Togari H LA - eng PT - Clinical Trial PT - Journal Article PL - United States TA - J Clin Ultrasound JT - Journal of clinical ultrasound : JCU JID - 0401663 SB - IM MH - Brain Diseases MH - Cysts MH - Female MH - Hemodynamics MH - Humans MH - Infant, Low Birth Weight MH - Infant, Newborn MH - Leukomalacia, Periventricular/*diagnostic imaging/*etiology MH - Male MH - Posterior Cerebral Artery/*diagnostic imaging/*physiology MH - Predictive Value of Tests MH - Prognosis MH - Regional Blood Flow MH - Ultrasonography EDAT- 2005/02/04 09:00 MHDA- 2005/03/30 09:00 CRDT- 2005/02/04 09:00 PHST- 2005/02/04 09:00 [pubmed] PHST- 2005/03/30 09:00 [medline] PHST- 2005/02/04 09:00 [entrez] AID - 10.1002/jcu.20082 [doi] PST - ppublish SO - J Clin Ultrasound. 2005 Jan;33(1):24-8. doi: 10.1002/jcu.20082.