PMID- 15690461
OWN - NLM
STAT- MEDLINE
DCOM- 20050524
LR  - 20151119
IS  - 0276-3478 (Print)
IS  - 0276-3478 (Linking)
VI  - 37
IP  - 1
DP  - 2005 Jan
TI  - Are there subgroups of bulimia nervosa based on comorbid psychiatric disorders?
PG  - 19-25
AB  - OBJECTIVE: The current study sought to determine whether there are subtypes of 
      bulimia nervosa (BN) differentiated by comorbid psychiatric disorders. METHOD: 
      Data on comorbid psychiatric diagnoses in female relatives of probands and 
      controls in the Collaborative Study of the Genetics of Alcoholism (COGA) who met 
      criteria for BN (as outlined in the 3rd Rev. ed. of the Diagnostic and 
      Statistical Manual of Mental Disorders) were analyzed using latent class 
      analysis. Resulting latent classes were compared on a variety of variables 
      related to impulsive behaviors and psychological functioning. RESULTS: The 
      best-fitting solution, a two-class model, yielded one class (72%) characterized 
      by substance dependence, depression, antisocial personality disorder (ASPD), and 
      anxiety disorders, and another characterized by depression. The highly comorbid 
      class had more suicidality, more daily smokers, sought help for emotional 
      problems, and had lower Global Assessment of Functioning (GAF) scores compared 
      with those in the comorbid depression only class. DISCUSSION: Latent class 
      findings suggest the existence of two classes of BN differentiated by substance 
      dependence, impulsive behaviors, and poorer psychological functioning.
CI  - 2004 by Wiley Periodicals, Inc.
FAU - Duncan, Alexis E
AU  - Duncan AE
AD  - Department of Psychiatry, Washington University School of Medicine, St. Louis, 
      Missouri 63108, USA.
FAU - Neuman, Rosalind J
AU  - Neuman RJ
FAU - Kramer, John
AU  - Kramer J
FAU - Kuperman, Samuel
AU  - Kuperman S
FAU - Hesselbrock, Victor
AU  - Hesselbrock V
FAU - Reich, Theodore
AU  - Reich T
FAU - Bucholz, Kathleen K
AU  - Bucholz KK
LA  - eng
GR  - U10AA08403/AA/NIAAA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Int J Eat Disord
JT  - The International journal of eating disorders
JID - 8111226
SB  - IM
MH  - Adult
MH  - Bulimia/*classification/genetics/*psychology
MH  - Case-Control Studies
MH  - Comorbidity
MH  - Diagnostic and Statistical Manual of Mental Disorders
MH  - Disruptive, Impulse Control, and Conduct Disorders
MH  - Female
MH  - Humans
MH  - Mental Disorders/*psychology
MH  - Middle Aged
MH  - Pedigree
MH  - Psychometrics
MH  - Substance-Related Disorders
EDAT- 2005/02/04 09:00
MHDA- 2005/05/25 09:00
CRDT- 2005/02/04 09:00
PHST- 2005/02/04 09:00 [pubmed]
PHST- 2005/05/25 09:00 [medline]
PHST- 2005/02/04 09:00 [entrez]
AID - 10.1002/eat.20066 [doi]
PST - ppublish
SO  - Int J Eat Disord. 2005 Jan;37(1):19-25. doi: 10.1002/eat.20066.