PMID- 1569211
OWN - NLM
STAT- MEDLINE
DCOM- 19920527
LR  - 20191028
IS  - 0197-1522 (Print)
IS  - 0197-1522 (Linking)
VI  - 13
IP  - 1
DP  - 1992
TI  - Radioimmunoassay measurement of albumin in urine is a valid method for monitoring 
      analbuminemia in rats.
PG  - 31-46
AB  - Plasma and urinary albumin levels, urinary creatinine and urine volumes were 
      measured at two-week intervals in Nagase analbuminemic rats (NAR) of either sex 
      at ages from 42 to 154 days. Age matched Sprague Dawley (SD) rats were used as 
      controls. Plasma concentrations of immunoreactive albumin (iALB) in NAR ranged 
      from 0.007 +/- 0.002 to 0.023 +/- 0.003 mg/ml, and were lower in younger rats. In 
      SD rats, plasma iALB concentrations ranged from 18.9 +/- 1.0 to 46.2 +/- 6.4 
      mg/ml. Urinary iALB output in NAR was less than 0.05 micrograms/mg creatinine 
      measured over a 24 hr period, whereas it was greater than 20 micrograms/mg 
      creatinine in the SD rats. Measurement of urine iALB concentrations in the NAR 
      colony appears to be a reliable and a non-invasive method for monitoring the 
      persistence of hypoalbuminemia.
FAU - Yaschuk, D M
AU  - Yaschuk DM
AD  - Department of Physiology, Faculty of Medicine, University of British Columbia, 
      Vancouver, Canada.
FAU - Sanker, J M
AU  - Sanker JM
FAU - Keeler, R
AU  - Keeler R
FAU - Wilson, N
AU  - Wilson N
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Immunoassay
JT  - Journal of immunoassay
JID - 8007167
RN  - 0 (Albumins)
RN  - 0 (Serum Albumin)
SB  - IM
MH  - Age Factors
MH  - Albumins/*deficiency
MH  - Albuminuria/blood/*urine
MH  - Animals
MH  - Evaluation Studies as Topic
MH  - Female
MH  - Male
MH  - Radioimmunoassay/*methods/statistics & numerical data
MH  - Rats
MH  - Rats, Mutant Strains
MH  - Sensitivity and Specificity
MH  - Serum Albumin/analysis
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
AID - 10.1080/15321819208019823 [doi]
PST - ppublish
SO  - J Immunoassay. 1992;13(1):31-46. doi: 10.1080/15321819208019823.