PMID- 15719040
OWN - NLM
STAT- MEDLINE
DCOM- 20061212
LR  - 20171116
IS  - 1671-167X (Print)
IS  - 1671-167X (Linking)
VI  - 37
IP  - 1
DP  - 2005 Feb 18
TI  - [The establishment and clinical application of multicolor fluorescence in situ 
      hybridization].
PG  - 45-7
AB  - OBJECTIVE: To establish a rapid and convenient method of multi-color fluorescence 
      in situ hybridization (FISH) on several different tissue samples: peripheral 
      blood samples, amniotic fluid, embryos and bone marrow samples. METHODS: FISH 
      analysis was carried out on different tissue samples, using probes specific for 
      chromosomes 13,18,21,X and Y or for BCR/ABL gene. RESULTS: FISH analysis could 
      reveal hybridization signals on metaphase chromosomes and interphase nuclei, it 
      is also possible to detect chromosome aberrations. CONCLUSION: Multi-color FISH 
      is clinically useful tool, which can be used as an adjunct to conventional 
      chromosome analysis for prenatal diagnosis , preimplantation genetic diagnosis 
      and diagnosis of leukemia.
FAU - Li, Qing
AU  - Li Q
AD  - Guangzhou Second People's Hospital, Guangzhou Research Institute of Obstetrics 
      and Gynecology, Guangzhou 510150, China. qinglicn@sina.com.cn
FAU - Sun, Xiao-fang
AU  - Sun XF
FAU - Chen, Xin-jie
AU  - Chen XJ
FAU - Kong, Shu
AU  - Kong S
FAU - Zheng, Yu-hong
AU  - Zheng YH
FAU - Huang, Yan-yi
AU  - Huang YY
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Beijing Da Xue Xue Bao Yi Xue Ban
JT  - Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health 
      sciences
JID - 101125284
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Pregnancy
MH  - Prenatal Diagnosis/*methods
EDAT- 2005/02/19 09:00
MHDA- 2006/12/13 09:00
CRDT- 2005/02/19 09:00
PHST- 2005/02/19 09:00 [pubmed]
PHST- 2006/12/13 09:00 [medline]
PHST- 2005/02/19 09:00 [entrez]
PST - ppublish
SO  - Beijing Da Xue Xue Bao Yi Xue Ban. 2005 Feb 18;37(1):45-7.