PMID- 15719382
OWN - NLM
STAT- MEDLINE
DCOM- 20050325
LR  - 20161124
IS  - 0022-4790 (Print)
IS  - 0022-4790 (Linking)
VI  - 89
IP  - 3
DP  - 2005 Mar 1
TI  - Multiple endocrine neoplasia type 1.
PG  - 143-50
AB  - Multiple endocrine neoplasia-1 (MEN-1) is an autosomal dominant inherited 
      syndrome that occurs due to inactivating mutations of the MEN1 gene locus, coding 
      for a tumor-suppressor protein, menin. The components of MEN-1 are 
      hyperparathyroidism due to multiple parathyroid adenomas, pancreatic 
      neuroendocrine tumors, and pituitary adenomas, in addition to some less common 
      neoplastic manifestations. Care of people with MEN-1 requires knowledge of the 
      problems that may arise, and the best approaches to detect and care for the 
      manifestations of this incurable, but manageable, disease.
CI  - (c) 2005 Wiley-Liss, Inc.
FAU - Doherty, Gerard M
AU  - Doherty GM
AD  - NW Thompson Professor of Surgery, University of Michigan, Ann Arbor, Michigan, 
      USA. gerardd@umich.edu
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - J Surg Oncol
JT  - Journal of surgical oncology
JID - 0222643
RN  - 0 (MEN1 protein, human)
RN  - 0 (Proto-Oncogene Proteins)
SB  - IM
MH  - Adenoma/diagnosis
MH  - Endosonography
MH  - Female
MH  - *Genes, Tumor Suppressor
MH  - Humans
MH  - Hyperparathyroidism/etiology
MH  - Insulinoma/diagnostic imaging/surgery
MH  - Male
MH  - *Multiple Endocrine Neoplasia Type 1/diagnosis/genetics/surgery
MH  - Neuroectodermal Tumors/diagnostic imaging
MH  - Pancreatic Neoplasms/diagnostic imaging/surgery
MH  - Parathyroid Neoplasms/diagnosis
MH  - Pituitary Neoplasms/surgery
MH  - Prolactinoma/surgery
MH  - Proto-Oncogene Proteins/*genetics
MH  - Tomography, Emission-Computed, Single-Photon
MH  - Tomography, X-Ray Computed
MH  - Vipoma/surgery
RF  - 35
EDAT- 2005/02/19 09:00
MHDA- 2005/03/26 09:00
CRDT- 2005/02/19 09:00
PHST- 2005/02/19 09:00 [pubmed]
PHST- 2005/03/26 09:00 [medline]
PHST- 2005/02/19 09:00 [entrez]
AID - 10.1002/jso.20181 [doi]
PST - ppublish
SO  - J Surg Oncol. 2005 Mar 1;89(3):143-50. doi: 10.1002/jso.20181.