PMID- 1576752
OWN - NLM
STAT- MEDLINE
DCOM- 19920610
LR  - 20190816
IS  - 0009-9163 (Print)
IS  - 0009-9163 (Linking)
VI  - 41
IP  - 4
DP  - 1992 Apr
TI  - Detection of subtle reciprocal translocations by fluorescence in situ 
      hybridization.
PG  - 169-74
AB  - Three different subtle reciprocal translocations were detected on long, 
      well-banded chromosomes. The same translocations were examined using fluorescence 
      in situ hybridization (FISH) with chromosome-specific libraries and unique DNA 
      sequences. Our findings show that FISH allows rapid and unequivocal detection and 
      characterization of this type of chromosome rearrangement. This approach is 
      especially useful for prenatal diagnosis when one of the parents is a balanced 
      carrier of such small fragment translocations.
FAU - Speleman, F
AU  - Speleman F
AD  - Department of Medical Genetics, University Hospital, Ghent, Belgium.
FAU - Van Roy, N
AU  - Van Roy N
FAU - Wiegant, J
AU  - Wiegant J
FAU - Verschraegen-Spae, M R
AU  - Verschraegen-Spae MR
FAU - Benoit, Y
AU  - Benoit Y
FAU - Govaert, P
AU  - Govaert P
FAU - Goossens, L
AU  - Goossens L
FAU - Leroy, J G
AU  - Leroy JG
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Denmark
TA  - Clin Genet
JT  - Clinical genetics
JID - 0253664
RN  - 0 (Fluorescent Dyes)
SB  - IM
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Fetus/abnormalities
MH  - Fluorescent Dyes
MH  - Humans
MH  - Infant
MH  - Male
MH  - *Nucleic Acid Hybridization
MH  - Pregnancy
MH  - Prenatal Diagnosis/methods
MH  - Translocation, Genetic/*genetics
EDAT- 1992/04/01 00:00
MHDA- 1992/04/01 00:01
CRDT- 1992/04/01 00:00
PHST- 1992/04/01 00:00 [pubmed]
PHST- 1992/04/01 00:01 [medline]
PHST- 1992/04/01 00:00 [entrez]
AID - 10.1111/j.1399-0004.1992.tb03657.x [doi]
PST - ppublish
SO  - Clin Genet. 1992 Apr;41(4):169-74. doi: 10.1111/j.1399-0004.1992.tb03657.x.