PMID- 15788355 OWN - NLM STAT- MEDLINE DCOM- 20051208 LR - 20221207 IS - 0301-4460 (Print) IS - 0301-4460 (Linking) VI - 32 IP - 1 DP - 2005 Jan-Feb TI - Validity of BMI as a measure of obesity in Australian white Caucasian and Australian Sri Lankan children. PG - 60-71 AB - BACKGROUND: Body mass index (BMI) is used to diagnose obesity. However, its ability to predict the percentage fat mass (%FM) reliably is doubtful. Therefore validity of BMI as a diagnostic tool of obesity is questioned. AIM: This study is focused on determining the ability of BMI-based cut-off values in diagnosing obesity among Australian children of white Caucasian and Sri Lankan origin. SUBJECTS AND METHODS: Height and weight was measured and BMI (W/H2) calculated. Total body water was determined by deuterium dilution technique and fat free mass and hence fat mass derived using age- and gender-specific constants. A %FM of 30% for girls and 20% for boys was considered as the criterion cut-off level for obesity. BMI-based obesity cut-offs described by the International Obesity Task Force (IOTF), CDC/NCHS centile charts and BMI-Z were validated against the criterion method. RESULTS: There were 96 white Caucasian and 42 Sri Lankan children. Of the white Caucasians, 19 (36%) girls and 29 (66%) boys, and of the Sri Lankans 7 (46%) girls and 16 (63%) boys, were obese based on %FM. The FM and BMI were closely associated in both Caucasians (r=0.81, P<0.001) and Sri Lankans (r=0.92, P<0.001). Percentage FM and BMI also had a lower but significant association. Obesity cut-off values recommended by IOTF failed to detect a single case of obesity in either group. However, NCHS and BMI-Z cut-offs detected cases of obesity with low sensitivity. CONCLUSIONS: BMI is a poor indicator of percentage fat and the commonly used cut-off values were not sensitive enough to detect cases of childhood obesity in this study. In order to improve the diagnosis of obesity, either BMI cut-off values should be revised to increase the sensitivity or the possibility of using other indirect methods of estimating the %FM should be explored. FAU - Wickramasinghe, V P AU - Wickramasinghe VP AD - Children's Nutrition Research Centre, Department of Paediatrics and Child Health, University of Queensland, Brisbane, Australia. FAU - Cleghorn, G J AU - Cleghorn GJ FAU - Edmiston, K A AU - Edmiston KA FAU - Murphy, A J AU - Murphy AJ FAU - Abbott, R A AU - Abbott RA FAU - Davies, P S W AU - Davies PS LA - eng PT - Journal Article PL - England TA - Ann Hum Biol JT - Annals of human biology JID - 0404024 RN - 0 (Biomarkers) SB - IM MH - Adolescent MH - Algorithms MH - Australia MH - Biomarkers MH - Body Height MH - *Body Mass Index MH - Body Weight MH - Child MH - Child, Preschool MH - Female MH - Humans MH - Male MH - Obesity/*diagnosis/ethnology MH - Sensitivity and Specificity MH - Sri Lanka MH - White People EDAT- 2005/03/25 09:00 MHDA- 2005/12/13 09:00 CRDT- 2005/03/25 09:00 PHST- 2005/03/25 09:00 [pubmed] PHST- 2005/12/13 09:00 [medline] PHST- 2005/03/25 09:00 [entrez] AID - M7YHQ0MP7KNVB3PU [pii] AID - 10.1080/03014460400027805 [doi] PST - ppublish SO - Ann Hum Biol. 2005 Jan-Feb;32(1):60-71. doi: 10.1080/03014460400027805.