PMID- 15791449
OWN - NLM
STAT- MEDLINE
DCOM- 20051004
LR  - 20061115
IS  - 0340-1200 (Print)
IS  - 0340-1200 (Linking)
VI  - 92
IP  - 4
DP  - 2005 Apr
TI  - Modeling the acceleration sensitive neurons in the pigeon optokinetic system.
PG  - 252-60
AB  - Recent physiological findings revealed that about one-third of motion-sensitive 
      neurons in the pigeon's pretectal nucleus encoded the acceleration of visual 
      motion. Here we propose a microcircuit hypothesis, in which the slow adaptive 
      depressions play a significant role in response generating, to account for the 
      origin of the three important properties of the acceleration-sensitive neurons: 
      the plateau-shaped speed-tuning curves, the opposite-signed after-responses 
      (OSARs) and the acceleration sensitivities. The flat plateau within the 
      speed-tuning curves and the OSARs to motion offset observed in experiments are 
      reproduced successfully in simulations, and the simulative responses of the 
      acceleration-sensitive neurons to step changes, ramp changes in stimulus speed 
      and sine wave modulations of stimulus speed are qualitatively consistent with 
      physiological observations. Thus, a biologically plausible substrate for the 
      neurons' classification and the origin of the three properties are provided.
FAU - Zhang, Chuan
AU  - Zhang C
AD  - State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, 
      Chinese Academy of Sciences, 15 Datun Road, Beijing, 100101, P.R. China.
FAU - Wang, Yun-Jiu
AU  - Wang YJ
FAU - Qi, Xiang-Lin
AU  - Qi XL
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050324
PL  - Germany
TA  - Biol Cybern
JT  - Biological cybernetics
JID - 7502533
SB  - IM
MH  - *Acceleration
MH  - Action Potentials/physiology/radiation effects
MH  - Animals
MH  - Columbidae/*physiology
MH  - Computer Simulation
MH  - *Models, Neurological
MH  - Neurons, Afferent/classification/*physiology
MH  - Nystagmus, Optokinetic/*physiology
MH  - Photic Stimulation/methods
MH  - Reaction Time/physiology/radiation effects
MH  - Time Factors
MH  - Visual Pathways/physiology
MH  - Visual Perception/physiology
EDAT- 2005/03/26 09:00
MHDA- 2005/10/05 09:00
CRDT- 2005/03/26 09:00
PHST- 2004/10/12 00:00 [received]
PHST- 2005/01/24 00:00 [accepted]
PHST- 2005/03/26 09:00 [pubmed]
PHST- 2005/10/05 09:00 [medline]
PHST- 2005/03/26 09:00 [entrez]
AID - 10.1007/s00422-005-0549-z [doi]
PST - ppublish
SO  - Biol Cybern. 2005 Apr;92(4):252-60. doi: 10.1007/s00422-005-0549-z. Epub 2005 Mar 
      24.