PMID- 15796997
OWN - NLM
STAT- MEDLINE
DCOM- 20050711
LR  - 20191210
IS  - 0378-1097 (Print)
IS  - 0378-1097 (Linking)
VI  - 245
IP  - 1
DP  - 2005 Apr 1
TI  - The prevalence of the Staphylococcus aureus tst gene among community- and 
      hospital-acquired strains and isolates from Wegener's Granulomatosis patients.
PG  - 185-9
AB  - To allow rapid identification of toxic shock syndrome toxin-1 (TSST-1)-producing 
      Staphylococcus aureus strains, a real-time PCR assay for the detection of the tst 
      gene, which encodes TSST-1, was developed. The assay was applied to S. aureus 
      isolates from patients with Wegener's Granulomatosis (WG), as well as isolates 
      that were classified as either community- (CA) or hospital-acquired (HA). No 
      significant difference in the percentage of tst-positive strains was observed 
      between isolates from WG patients and CA isolates (24% and 25%, respectively). In 
      contrast, only 14% of the HA isolates were tst-positive (p<0.05). Investigation 
      of the clonal relationship between tst-positive CA and HA strains could indicated 
      the recent emergence of a virulent S. aureus clone in the community.
FAU - Deurenberg, Ruud H
AU  - Deurenberg RH
AD  - Department of Medical Microbiology, University Hospital Maastricht, PO Box 5800, 
      6202 AZ Maastricht, The Netherlands.
FAU - Nieuwenhuis, Rutger F
AU  - Nieuwenhuis RF
FAU - Driessen, Christel
AU  - Driessen C
FAU - London, Nancy
AU  - London N
FAU - Stassen, Frank R
AU  - Stassen FR
FAU - van Tiel, Frank H
AU  - van Tiel FH
FAU - Stobberingh, Ellen E
AU  - Stobberingh EE
FAU - Vink, Cornelis
AU  - Vink C
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - England
TA  - FEMS Microbiol Lett
JT  - FEMS microbiology letters
JID - 7705721
RN  - 0 (Bacterial Toxins)
RN  - 0 (DNA, Bacterial)
RN  - 0 (Enterotoxins)
RN  - 0 (Superantigens)
RN  - 0 (enterotoxin F, Staphylococcal)
SB  - IM
MH  - Bacterial Toxins/*genetics/metabolism
MH  - Community-Acquired Infections/*epidemiology/microbiology
MH  - Cross Infection/*epidemiology/microbiology
MH  - DNA, Bacterial/analysis
MH  - Electrophoresis, Gel, Pulsed-Field
MH  - Enterotoxins/*genetics/metabolism
MH  - Granulomatosis with Polyangiitis/*epidemiology/microbiology
MH  - Humans
MH  - Polymerase Chain Reaction/*methods
MH  - Prevalence
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Staphylococcal Infections/microbiology
MH  - Staphylococcus aureus/genetics/isolation & purification/*pathogenicity
MH  - Superantigens/*genetics/metabolism
MH  - Virulence
EDAT- 2005/03/31 09:00
MHDA- 2005/07/12 09:00
CRDT- 2005/03/31 09:00
PHST- 2005/01/10 00:00 [received]
PHST- 2005/03/01 00:00 [revised]
PHST- 2005/03/03 00:00 [accepted]
PHST- 2005/03/31 09:00 [pubmed]
PHST- 2005/07/12 09:00 [medline]
PHST- 2005/03/31 09:00 [entrez]
AID - S0378-1097(05)00147-3 [pii]
AID - 10.1016/j.femsle.2005.03.002 [doi]
PST - ppublish
SO  - FEMS Microbiol Lett. 2005 Apr 1;245(1):185-9. doi: 10.1016/j.femsle.2005.03.002.