PMID- 15801500
OWN - NLM
STAT- MEDLINE
DCOM- 20050426
LR  - 20111117
IS  - 0264-0414 (Print)
IS  - 0264-0414 (Linking)
VI  - 22
IP  - 11-12
DP  - 2004 Nov-Dec
TI  - Skeletal muscle glycogen concentration and metabolic responses following a high 
      glycaemic carbohydrate breakfast.
PG  - 1065-71
AB  - The purpose of this study was to examine the influence of a carbohydrate-rich 
      meal on post-prandial metabolic responses and skeletal muscle glycogen 
      concentration. After an overnight fast, eight male recreational/club endurance 
      runners ingested a carbohydrate (CHO) meal (2.5 g CHO x kg(-1) body mass) and 
      biopsies were obtained from the vastus lateralis muscle before and 3 h after the 
      meal. Ingestion of the meal resulted in a 10.6 +/- 2.5% (P < 0.05) increase in 
      muscle glycogen concentration (pre-meal vs post-meal: 314.0 +/- 33.9 vs 347.3 +/- 
      31.3 mmol x kg(-1) dry weight). Three hours after ingestion, mean serum insulin 
      concentrations had not returned to pre-feeding values (0 min vs 180 min: 45 +/- 4 
      vs 143 +/- 21 pmol x l(-1)). On a separate occasion, six similar individuals 
      ingested the meal or fasted for a further 3 h during which time expired air 
      samples were collected to estimate the amount of carbohydrate oxidized over the 3 
      h post-prandial period. It was estimated that about 20% of the carbohydrate 
      consumed was converted into muscle glycogen, and about 12 % was oxidized. We 
      conclude that a meal providing 2.5 g CHO x kg(-1) body mass can increase muscle 
      glycogen stores 3 h after ingestion. However, an estimated 67% of the 
      carbohydrate ingested was unaccounted for and this may have been stored as liver 
      glycogen and/or still be in the gastrointestinal tract.
FAU - Chryssanthopoulos, Costas
AU  - Chryssanthopoulos C
AD  - Human Muscle Metabolism Research Group, School of Sport and Exercise Sciences, 
      Loughborough University, Loughborough LE11 3TU, UK. chryssan@phed.uoa.gr
FAU - Williams, Clyde
AU  - Williams C
FAU - Nowitz, Andrea
AU  - Nowitz A
FAU - Bogdanis, Gregory
AU  - Bogdanis G
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - J Sports Sci
JT  - Journal of sports sciences
JID - 8405364
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Insulin)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Dietary Carbohydrates/*metabolism
MH  - Energy Metabolism/physiology
MH  - Fatty Acids, Nonesterified/blood
MH  - Glycogen/*metabolism
MH  - Humans
MH  - Insulin/blood
MH  - Male
MH  - Muscle, Skeletal/*metabolism/*pathology
MH  - Oxygen Consumption/physiology
MH  - Postprandial Period/*physiology
MH  - Reference Values
MH  - Time Factors
EDAT- 2005/04/02 09:00
MHDA- 2005/04/27 09:00
CRDT- 2005/04/02 09:00
PHST- 2005/04/02 09:00 [pubmed]
PHST- 2005/04/27 09:00 [medline]
PHST- 2005/04/02 09:00 [entrez]
AID - 10.1080/02640410410001730007 [doi]
PST - ppublish
SO  - J Sports Sci. 2004 Nov-Dec;22(11-12):1065-71. doi: 10.1080/02640410410001730007.