PMID- 15803282
OWN - NLM
STAT- MEDLINE
DCOM- 20060118
LR  - 20181113
IS  - 0957-4530 (Print)
IS  - 0957-4530 (Linking)
VI  - 16
IP  - 4
DP  - 2005 Apr
TI  - Preparation and characterization of bioactive collagen/wollastonite composite 
      scaffolds.
PG  - 361-5
AB  - A novel biodegradable collagen/wollastonite composite was prepared as 
      three-dimensional scaffolds by freeze-drying method. Scanning electron microscope 
      (SEM) micrographs of scaffolds showed a continuous structure of interconnected 
      pores, and pore size was about 100 microm. The tensile strength of the scaffolds 
      was improved by incorporation of wollastonite and the in vitro bioactivity of the 
      scaffolds was evaluated by examining the hydroxyapatite (HA) deposition on their 
      surface in simulated body fluid (SBF). After soaking in SBF for 7 days, collagen 
      reconstituted to fibers and HA nodules formed on collagen fibers. The result 
      suggests that the incorporation of wollastonite could improve the mechanical 
      strength and the in vitro bioactivity of the composite. The scaffolds could be a 
      potential biomaterial for bone tissue engineering.
FAU - Li, Xiaoke
AU  - Li X
AD  - Biomaterials and Tissue Engineering Research Center, Shanghai Institute of 
      Ceramics, Chinese Academy of Sciences, Shanghai, People's Republic of China.
FAU - Chang, Jiang
AU  - Chang J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Mater Sci Mater Med
JT  - Journal of materials science. Materials in medicine
JID - 9013087
RN  - 0 (Biocompatible Materials)
RN  - 0 (Calcium Compounds)
RN  - 0 (Silicates)
RN  - 0 (Solutions)
RN  - 9007-34-5 (Collagen)
RN  - S4255P4G5M (calcium silicate)
SB  - IM
MH  - Biocompatible Materials/*chemistry/metabolism
MH  - Bone and Bones/physiology
MH  - Calcium Compounds/*chemistry/metabolism
MH  - Collagen/*chemistry/metabolism
MH  - Freeze Drying
MH  - Microscopy, Electron, Scanning
MH  - Silicates/*chemistry/metabolism
MH  - Solutions
MH  - Tensile Strength
MH  - *Tissue Engineering
EDAT- 2005/04/02 09:00
MHDA- 2006/01/19 09:00
CRDT- 2005/04/02 09:00
PHST- 2004/01/29 00:00 [received]
PHST- 2004/10/19 00:00 [accepted]
PHST- 2005/04/02 09:00 [pubmed]
PHST- 2006/01/19 09:00 [medline]
PHST- 2005/04/02 09:00 [entrez]
AID - 10.1007/s10856-005-0636-7 [doi]
PST - ppublish
SO  - J Mater Sci Mater Med. 2005 Apr;16(4):361-5. doi: 10.1007/s10856-005-0636-7.