PMID- 15806507 OWN - NLM STAT- MEDLINE DCOM- 20050623 LR - 20190922 IS - 8755-7223 (Print) IS - 8755-7223 (Linking) VI - 21 IP - 2 DP - 2005 Mar-Apr TI - The ethics of heparin administration to the potential non-heart-beating organ donor. PG - 97-102 AB - The increasing need and limited sources for organs has stimulated a renewed interest in non-heart-beating organ donation (NHBOD). NHBOD is the donation of organs from cadavers that have been declared dead by cardiopulmonary criteria. Emerging protocols for heparin administration to the potential non-heart-beating organ donor (NHBD) deserve scrutiny. This topic is presented within a limited discussion of organ donation in general. The definition of death has been refined to its present state because of the need for clear parameters in light of a desire to procure organs for transplant. The administration of heparin to the NHBD is intended to prevent the formation of blood clots in the kidneys and liver. Heparin at high doses is clearly not given for the benefit of the patient, and some professionals are concerned that administration may hasten death. Nurses are guided by codes that require the consideration of the ethical principles of autonomy, informed consent, beneficence, and justice while providing compassionate care. An eagerness to procure viable organs for positive transplant outcomes must not be the guiding force in protocols that allow the administration of heparin to the potential NHBD. Heparin administration is supported for these donors within specific parameters. FAU - Motta, Elizabeth D AU - Motta ED AD - Department of Nursing, Rhode Island College, Providence 02908, USA. LA - eng PT - Journal Article PT - Review PL - United States TA - J Prof Nurs JT - Journal of professional nursing : official journal of the American Association of Colleges of Nursing JID - 8511298 RN - 0 (Anticoagulants) RN - 9005-49-6 (Heparin) SB - IM MH - Anticoagulants/*administration & dosage MH - Attitude to Health MH - Brain Death/diagnosis MH - *Cadaver MH - Clinical Protocols/standards MH - Codes of Ethics MH - Decision Making, Organizational MH - Family/psychology MH - Heart Arrest/diagnosis MH - Heparin/*administration & dosage MH - Humans MH - Informed Consent/ethics MH - Nurse's Role MH - Patient Advocacy/ethics MH - Patient Selection/ethics MH - Principle-Based Ethics MH - Public Opinion MH - Social Perception MH - Tissue Donors/*ethics MH - Tissue and Organ Harvesting/*ethics/methods MH - Tissue and Organ Procurement/*ethics/organization & administration RF - 13 OID - KIE: 124779 OTO - KIE OT - Health Care and Public Health GN - KIE: KIE Bib: organ and tissue donation EDAT- 2005/04/05 09:00 MHDA- 2005/06/24 09:00 CRDT- 2005/04/05 09:00 PHST- 2005/04/05 09:00 [pubmed] PHST- 2005/06/24 09:00 [medline] PHST- 2005/04/05 09:00 [entrez] AID - S8755722305000190 [pii] AID - 10.1016/j.profnurs.2005.01.005 [doi] PST - ppublish SO - J Prof Nurs. 2005 Mar-Apr;21(2):97-102. doi: 10.1016/j.profnurs.2005.01.005.