PMID- 15812754
OWN - NLM
STAT- MEDLINE
DCOM- 20050922
LR  - 20191109
IS  - 1071-9164 (Print)
IS  - 1071-9164 (Linking)
VI  - 11
IP  - 3
DP  - 2005 Apr
TI  - Treating heart failure with enhanced external counterpulsation (EECP): design of 
      the Prospective Evaluation of EECP in Heart Failure (PEECH) trial.
PG  - 240-5
AB  - BACKGROUND: Enhanced external counterpulsation (EECP) treatment can improve 
      exercise tolerance in patients with ischemic heart disease; however, the possible 
      benefits of EECP in patients with stable heart failure (HF) and left ventricular 
      dysfunction (LVD) are unclear. An open pilot study showed significant increases 
      in exercise tolerance in HF patients undergoing EECP. Thus a larger, controlled 
      study of EECP in patients with stable HF (New York Heart Association [NYHA] 
      classes II and III) and LVD was undertaken. METHODS AND RESULTS: The PEECH trial 
      is a controlled, randomized, single-blind, parallel-group, multicenter study of 
      187 patients with symptomatic but stable HF (NYHA classes II and III) and an LV 
      ejection fraction < or =35% was designed to assess the efficiency of EECP in 
      patients with stable HF. Medical therapy is optimized in all patients based on 
      the recommendations of the Heart Failure Society of America ("Usual Care"), and 
      then randomized between 2 treatment groups; UC or EECP (35 hours over 7 weeks). 
      CONCLUSION: Efficacy measures include standard exercise tolerance tests on a 
      treadmill (modified Naughton protocol), with measurements of peak oxygen uptake 
      and exercise duration time; quality of life questionnaires; NYHA classification; 
      and neurohormonal markers of HF.
FAU - Feldman, Arthur M
AU  - Feldman AM
AD  - Department of Medicine, Jefferson Medical College, 1025 Walnut Street, 
      Philadelphia, PA 19607, USA.
FAU - Silver, Marc A
AU  - Silver MA
FAU - Francis, Gary S
AU  - Francis GS
FAU - De Lame, Paul-Andre
AU  - De Lame PA
FAU - Parmley, William W
AU  - Parmley WW
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PL  - United States
TA  - J Card Fail
JT  - Journal of cardiac failure
JID - 9442138
SB  - IM
MH  - Counterpulsation/*methods
MH  - Exercise Test
MH  - Exercise Tolerance/physiology
MH  - Heart Failure/physiopathology/*therapy
MH  - Humans
MH  - Oxygen Consumption/physiology
MH  - Patient Selection
MH  - Quality of Life
MH  - Randomized Controlled Trials as Topic/methods
MH  - Single-Blind Method
MH  - Surveys and Questionnaires
EDAT- 2005/04/07 09:00
MHDA- 2005/09/24 09:00
CRDT- 2005/04/07 09:00
PHST- 2005/04/07 09:00 [pubmed]
PHST- 2005/09/24 09:00 [medline]
PHST- 2005/04/07 09:00 [entrez]
AID - S1071916404009005 [pii]
AID - 10.1016/j.cardfail.2004.10.001 [doi]
PST - ppublish
SO  - J Card Fail. 2005 Apr;11(3):240-5. doi: 10.1016/j.cardfail.2004.10.001.