PMID- 1582051
OWN - NLM
STAT- MEDLINE
DCOM- 19920618
LR  - 20191028
IS  - 0009-9155 (Print)
IS  - 0009-9155 (Linking)
VI  - 23
IP  - 2
DP  - 1992 Apr
TI  - Continuous, generalized, high-voltage fast activity and FIRDA in two children.
PG  - 68-71
AB  - The EEG pattern of continuous, generalized, high-voltage fast rhythms without any 
      reaction to eye-opening/closure, photic stimulation, or the sleep-awaking cycle 
      was previously reported to be characteristic of infantile neuroaxonal dystrophy 
      (INAD). However, we have observed such fast activity in one child with INAD and 
      one with Menkes' kinky-hair syndrome. They both exhibited severe psychomotor 
      disturbance, and their EEGs also included "frontal intermittent rhythmic delta 
      activity (FIRDA)," a nonspecific EEG finding suggestive of organic 
      encephalopathy. Since the continuous, generalized, high-voltage fast activity had 
      features suggestive of spindles in both children, this EEG pattern is thought to 
      actually represent "extreme spindles," and nonspecifically to indicate widespread 
      organic brain damage.
FAU - Mutoh, K
AU  - Mutoh K
AD  - Department of Pediatrics, Faculty of Medicine, Kyoto University, Japan.
FAU - Okuno, T
AU  - Okuno T
FAU - Ito, M
AU  - Ito M
FAU - Fujii, T
AU  - Fujii T
FAU - Mikawa, H
AU  - Mikawa H
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Clin Electroencephalogr
JT  - Clinical EEG (electroencephalography)
JID - 0236454
SB  - IM
MH  - Cerebral Cortex/physiopathology
MH  - Child
MH  - Child, Preschool
MH  - *Delta Rhythm
MH  - *Electroencephalography
MH  - Epilepsy, Generalized/diagnosis/*physiopathology
MH  - Evoked Potentials/physiology
MH  - Frontal Lobe/*physiopathology
MH  - Humans
MH  - Male
MH  - Menkes Kinky Hair Syndrome/diagnosis/*physiopathology
MH  - Pantothenate Kinase-Associated Neurodegeneration/diagnosis/*physiopathology
MH  - Photic Stimulation
EDAT- 1992/04/01 00:00
MHDA- 1992/04/01 00:01
CRDT- 1992/04/01 00:00
PHST- 1992/04/01 00:00 [pubmed]
PHST- 1992/04/01 00:01 [medline]
PHST- 1992/04/01 00:00 [entrez]
AID - 10.1177/155005949202300205 [doi]
PST - ppublish
SO  - Clin Electroencephalogr. 1992 Apr;23(2):68-71. doi: 10.1177/155005949202300205.