PMID- 15820957
OWN - NLM
STAT- MEDLINE
DCOM- 20060525
LR  - 20131121
IS  - 1592-8721 (Electronic)
IS  - 0390-6078 (Linking)
VI  - 90
IP  - 4
DP  - 2005 Apr
TI  - The incidence of submicroscopic deletions in reciprocal translocations is similar 
      in acute myeloid leukemia, BCR-ABL positive acute lymphoblastic leukemia, and 
      chronic myeloid leukemia.
PG  - 558-9
AB  - We compared the incidence of submicroscopic deletions accompanying balanced 
      translocations using interphase fluorescence in situ hybridization (FISH) in 245 
      patients with chronic myeloid leukemia (CML), 79 patients with acute 
      lymphoblastic leukemia (ALL) and BCR-ABL (n=70) or MLL rearrangements (n=29), and 
      412 patients with acute myeloid leukemia (AML) with CBFB-MYH11 (n=122), 
      PML-RARalpha (n=108), AML1-ETO (n=112), or MLL rearrangements (n=98). The 
      incidence of submicroscopic deletions was 2-9% depending on the entity.
FAU - Bacher, Ulrike
AU  - Bacher U
FAU - Schnittger, Susanne
AU  - Schnittger S
FAU - Kern, Wolfgang
AU  - Kern W
FAU - Hiddemann, Wolfgang
AU  - Hiddemann W
FAU - Haferlach, Torsten
AU  - Haferlach T
FAU - Schoch, Claudia
AU  - Schoch C
LA  - eng
PT  - Letter
PL  - Italy
TA  - Haematologica
JT  - Haematologica
JID - 0417435
RN  - EC 2.7.10.2 (Fusion Proteins, bcr-abl)
SB  - IM
MH  - Acute Disease
MH  - *Chromosome Deletion
MH  - Fusion Proteins, bcr-abl/*metabolism
MH  - Humans
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics
MH  - Leukemia, Myeloid/*genetics
MH  - Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics
MH  - Reproducibility of Results
MH  - Translocation, Genetic
EDAT- 2005/04/12 09:00
MHDA- 2006/05/26 09:00
CRDT- 2005/04/12 09:00
PHST- 2005/04/12 09:00 [pubmed]
PHST- 2006/05/26 09:00 [medline]
PHST- 2005/04/12 09:00 [entrez]
PST - ppublish
SO  - Haematologica. 2005 Apr;90(4):558-9.