PMID- 15821989
OWN - NLM
STAT- MEDLINE
DCOM- 20050712
LR  - 20211203
IS  - 0167-4412 (Print)
IS  - 0167-4412 (Linking)
VI  - 56
IP  - 6
DP  - 2004 Dec
TI  - Promotion of photomorphogenesis by COP1.
PG  - 905-15
AB  - CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) represses photomorphogenesis in darkness 
      by targeting nuclear-localized transcription factors to proteasome-mediated 
      degradation. Upon light exposure, COP1 migrates to the cytosol allowing 
      photomorphogenesis to proceed but the residual nuclear pool down-regulates light 
      signaling mediated by phytochrome A. Here we show that weak alleles of cop1 
      exhibit reverse photomorphogenic responses i.e. reduced rather than enhanced 
      cotyledon unfolding under red light compared to darkness. Conversely, COP1 
      overexpressors which de-etiolate poorly under blue or far-red light, showed 
      enhanced photomorphogenesis under red light. The positive relationship between 
      COP1 and photomorphogenic response required phytochrome B. Thus, genetic 
      manipulation of COP1 levels differentially affects phytochrome A- compared to 
      phytochrome B-mediated responses. We hypothesize that COP1 could be involved in 
      degradation of negative regulators of photomorphogenesis or in transcriptional 
      activation, as observed for some E3 ligases in mammalian development.
FAU - Boccalandro, Hernan E
AU  - Boccalandro HE
AD  - I.F.E.V.A., Faculty of Agronomy, University of Buenos Aires, Av. San Martin 4453, 
      1417, Buenos Aires, Argentina.
FAU - Rossi, Maria C
AU  - Rossi MC
FAU - Saijo, Yusuke
AU  - Saijo Y
FAU - Deng, Xing-Wang
AU  - Deng XW
FAU - Casal, Jorge J
AU  - Casal JJ
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050407
PL  - Netherlands
TA  - Plant Mol Biol
JT  - Plant molecular biology
JID - 9106343
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (PHYA protein, Arabidopsis)
RN  - 0 (PHYB protein, Arabidopsis)
RN  - 0 (Phytochrome A)
RN  - 0 (Transcription Factors)
RN  - 11121-56-5 (Phytochrome)
RN  - 136250-22-1 (Phytochrome B)
RN  - EC 2.3.2.27 (AT2G32950 protein, Arabidopsis)
RN  - EC 2.3.2.27 (Ubiquitin-Protein Ligases)
RN  - EC 2.7.11.1 (Protein Serine-Threonine Kinases)
SB  - IM
MH  - Arabidopsis/genetics/growth & development/*radiation effects
MH  - Arabidopsis Proteins/genetics/*physiology
MH  - Hypocotyl/genetics/growth & development/radiation effects
MH  - Light
MH  - Models, Biological
MH  - Morphogenesis/genetics/*radiation effects
MH  - Mutation
MH  - Photoreceptor Cells/physiology
MH  - Phytochrome/genetics/physiology
MH  - Phytochrome A
MH  - Phytochrome B
MH  - Protein Serine-Threonine Kinases/genetics/physiology
MH  - Transcription Factors/genetics/physiology
MH  - Ubiquitin-Protein Ligases/genetics/*physiology
EDAT- 2005/04/12 09:00
MHDA- 2005/07/13 09:00
CRDT- 2005/04/12 09:00
PHST- 2004/08/31 00:00 [received]
PHST- 2004/11/06 00:00 [accepted]
PHST- 2005/04/12 09:00 [pubmed]
PHST- 2005/07/13 09:00 [medline]
PHST- 2005/04/12 09:00 [entrez]
AID - 10.1007/s11103-004-5919-8 [doi]
PST - ppublish
SO  - Plant Mol Biol. 2004 Dec;56(6):905-15. doi: 10.1007/s11103-004-5919-8. Epub 2005 
      Apr 7.