PMID- 15825000 OWN - NLM STAT- MEDLINE DCOM- 20060724 LR - 20071114 IS - 1537-6591 (Electronic) IS - 1058-4838 (Linking) VI - 40 IP - 7 DP - 2005 Apr 1 TI - The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy. PG - 1049-52 AB - This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis. FAU - Shelburne, Samuel A 3rd AU - Shelburne SA 3rd AD - Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas, USA. samuels@bcm.tmc.edu FAU - Darcourt, Jorge AU - Darcourt J FAU - White, A Clinton Jr AU - White AC Jr FAU - Greenberg, Stephen B AU - Greenberg SB FAU - Hamill, Richard J AU - Hamill RJ FAU - Atmar, Robert L AU - Atmar RL FAU - Visnegarwala, Fehmida AU - Visnegarwala F LA - eng GR - T32-AI055413/AI/NIAID NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. DEP - 20050301 PL - United States TA - Clin Infect Dis JT - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JID - 9203213 RN - 0 (Anti-HIV Agents) SB - IM MH - Acquired Immunodeficiency Syndrome/*complications MH - Anti-HIV Agents/adverse effects MH - Antiretroviral Therapy, Highly Active/*adverse effects MH - Cryptococcosis/*etiology MH - Humans MH - Inflammation/*chemically induced/diagnosis/*immunology MH - Recurrence EDAT- 2005/04/13 09:00 MHDA- 2006/07/25 09:00 CRDT- 2005/04/13 09:00 PHST- 2004/08/24 00:00 [received] PHST- 2004/11/17 00:00 [accepted] PHST- 2005/04/13 09:00 [pubmed] PHST- 2006/07/25 09:00 [medline] PHST- 2005/04/13 09:00 [entrez] AID - CID34816 [pii] AID - 10.1086/428618 [doi] PST - ppublish SO - Clin Infect Dis. 2005 Apr 1;40(7):1049-52. doi: 10.1086/428618. Epub 2005 Mar 1.