PMID- 15828222
OWN - NLM
STAT- MEDLINE
DCOM- 20050527
LR  - 20110727
IS  - 0047-1852 (Print)
IS  - 0047-1852 (Linking)
VI  - 63
IP  - 4
DP  - 2005 Apr
TI  - [PPARs target genes].
PG  - 573-7
AB  - PPAR(alpha, beta/delta, gamma) are ligand-dependent nuclear receptors and 
      regulate homeostasis, cell proliferation/differentiation and associate with 
      hypolipidemia, atherosclerosis, diabetes, and obesity. Through heterodimerization 
      with retinoid X receptors (RXRs), PPARs bind the same consensus response element, 
      formed by a direct repeat of two AGGTCA hexamers separated by one base. Recently, 
      many PPAR direct and indirect target genes have been reported. Here, we summarize 
      the PPAR direct/indirect target genes, and their functions related to lipid 
      metabolism, adipocyte differentiation.
FAU - Takada, Ichiro
AU  - Takada I
AD  - Nuclear Signaling, Institute of Molecular and Cellular Biosciences, University of 
      Tokyo.
FAU - Kato, Shigeaki
AU  - Kato S
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Rinsho
JT  - Nihon rinsho. Japanese journal of clinical medicine
JID - 0420546
RN  - 0 (Fatty Acids)
RN  - 0 (Peroxisome Proliferator-Activated Receptors)
RN  - 0 (Receptors, Cytoplasmic and Nuclear)
SB  - IM
MH  - Animals
MH  - Fatty Acids/metabolism
MH  - Gene Expression Regulation
MH  - Lipid Metabolism
MH  - Peroxisome Proliferator-Activated Receptors/*physiology
MH  - Receptors, Cytoplasmic and Nuclear/*genetics
RF  - 21
EDAT- 2005/04/15 09:00
MHDA- 2005/05/28 09:00
CRDT- 2005/04/15 09:00
PHST- 2005/04/15 09:00 [pubmed]
PHST- 2005/05/28 09:00 [medline]
PHST- 2005/04/15 09:00 [entrez]
PST - ppublish
SO  - Nihon Rinsho. 2005 Apr;63(4):573-7.