PMID- 15831655
OWN - NLM
STAT- MEDLINE
DCOM- 20050517
LR  - 20191210
IS  - 1468-201X (Electronic)
IS  - 1355-6037 (Print)
IS  - 1355-6037 (Linking)
VI  - 91
IP  - 5
DP  - 2005 May
TI  - Late outcome of Senning and Mustard procedures for correction of transposition of 
      the great arteries.
PG  - 652-6
AB  - OBJECTIVES: To evaluate late mortality and morbidity after an atrial switch 
      procedure for correction of transposition of the great arteries (TGA) and to 
      assess predictive factors for adverse outcome. SETTING: Tertiary referral centre. 
      DESIGN AND PATIENTS: Retrospective follow up study of 137 patients surviving 
      hospitalisation for TGA atrial switch procedure (Mustard or Senning) in a single 
      institution and divided into two groups (simple and complex) depending on 
      presurgical anatomy. Several surgical and follow up factors were evaluated during 
      16.7 (5.6) years' follow up. RESULTS: Late mortality was 5.1% (95% confidence 
      interval 1.37% to 8.84%) with sudden death as the most common cause. No 
      significant difference was found between Mustard and Senning procedures and 
      between the complex and simple groups in terms of mortality. Independent 
      predictive factors for late mortality were a history of supraventricular 
      tachyarrhythmias and advanced New York Heart Association (NYHA) functional class 
      during follow up. A very common finding was development of sinus node dysfunction 
      (47.6%), which had no influence on mortality. There was little need for 
      reintervention (5.1%) and relatively few cases of right ventricular systolic 
      dysfunction (14.6%). During follow up, most patients (96.2%) were in NYHA 
      functional class I-II. CONCLUSIONS: Overall long term outcomes of patients with 
      atrial repair of TGA in the present era are encouraging in terms of late 
      mortality and quality of life. Nevertheless, better outcomes may be offered 
      through improved diagnostic methods for right ventricular function and better 
      management of supraventricular tachyarrhythmias.
FAU - Dos, L
AU  - Dos L
AD  - Department of General Cardiology, Hospital Materno-Infantil Vall d'Hebron, 
      Barcelona, Spain.
FAU - Teruel, L
AU  - Teruel L
FAU - Ferreira, I J
AU  - Ferreira IJ
FAU - Rodriguez-Larrea, J
AU  - Rodriguez-Larrea J
FAU - Miro, L
AU  - Miro L
FAU - Girona, J
AU  - Girona J
FAU - Albert, D C
AU  - Albert DC
FAU - Goncalves, A
AU  - Goncalves A
FAU - Murtra, M
AU  - Murtra M
FAU - Casaldaliga, J
AU  - Casaldaliga J
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - England
TA  - Heart
JT  - Heart (British Cardiac Society)
JID - 9602087
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Arrhythmias, Cardiac/etiology
MH  - Cardiac Surgical Procedures/*mortality
MH  - Child
MH  - Child, Preschool
MH  - Death, Sudden, Cardiac/etiology
MH  - Echocardiography/methods
MH  - Female
MH  - Humans
MH  - Infant
MH  - Male
MH  - Multivariate Analysis
MH  - Quality of Life
MH  - Reoperation/statistics & numerical data
MH  - Retrospective Studies
MH  - Transposition of Great Vessels/diagnostic imaging/mortality/*surgery
PMC - PMC1768896
EDAT- 2005/04/16 09:00
MHDA- 2005/05/18 09:00
PMCR- 2008/05/01
CRDT- 2005/04/16 09:00
PHST- 2005/04/16 09:00 [pubmed]
PHST- 2005/05/18 09:00 [medline]
PHST- 2005/04/16 09:00 [entrez]
PHST- 2008/05/01 00:00 [pmc-release]
AID - 91/5/652 [pii]
AID - 0910652 [pii]
AID - 10.1136/hrt.2003.029769 [doi]
PST - ppublish
SO  - Heart. 2005 May;91(5):652-6. doi: 10.1136/hrt.2003.029769.