PMID- 15831796
OWN - NLM
STAT- MEDLINE
DCOM- 20050930
LR  - 20130926
IS  - 8750-7587 (Print)
IS  - 0161-7567 (Linking)
VI  - 99
IP  - 2
DP  - 2005 Aug
TI  - Ingestion of a high-glycemic index meal increases muscle glycogen storage at rest 
      but augments its utilization during subsequent exercise.
PG  - 707-14
AB  - The aim of this study was to compare the effect of preexercise breakfast 
      containing high- and low-glycemic index (GI) carbohydrate (CHO) (2.5g CHO/kg body 
      mass) on muscle glycogen metabolism. On two occasions, 14 days apart, seven 
      trained men ran at 71% maximal oxygen uptake for 30 min on a treadmill. Three 
      hours before exercise, in a randomized order, subjects consumed either 
      isoenergetic high- (HGI) or low-GI (LGI) CHO breakfasts that provided (per 70 kg 
      body mass) 3.43 MJ energy, 175 g CHO, 21 g protein, and 4 g fat. The incremental 
      areas under the 3-h plasma glucose and serum insulin response curves after the 
      HGI meal were 3.9- (P < 0.05) and 1.4-fold greater (P < 0.001), respectively, 
      than those after the LGI meal. During the 3-h postprandial period, muscle 
      glycogen concentration increased by 15% (P < 0.05) after the HGI meal but 
      remained unchanged after the LGI meal. Muscle glycogen utilization during 
      exercise was greater in the HGI (129.1 +/- 16.1 mmol/kg dry mass) compared with 
      the LGI (87.9 +/- 15.1 mmol/kg dry mass; P < 0.01) trial. Although the LGI meal 
      contributed less CHO to muscle glycogen synthesis in the 3-h postprandial period 
      compared with the HGI meal, a sparing of muscle glycogen utilization during 
      subsequent exercise was observed in the LGI trial, most likely as a result of 
      better maintained fat oxidation.
FAU - Wee, Shiou-Liang
AU  - Wee SL
AD  - School of Sport and Exercise Sciences, Loughborough University, Loughborough, 
      Leicestershire LE11 3TU, UK.
FAU - Williams, Clyde
AU  - Williams C
FAU - Tsintzas, Kostas
AU  - Tsintzas K
FAU - Boobis, Leslie
AU  - Boobis L
LA  - eng
PT  - Clinical Trial
PT  - Controlled Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050414
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Dietary Carbohydrates)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Adaptation, Physiological/physiology
MH  - Adult
MH  - Dietary Carbohydrates/*metabolism
MH  - Exercise Test
MH  - Glycemic Index/*physiology
MH  - Glycogen/*metabolism
MH  - Humans
MH  - Male
MH  - Metabolic Clearance Rate
MH  - Muscle, Skeletal/*physiology
MH  - Physical Exertion/*physiology
MH  - Postprandial Period/*physiology
MH  - Rest/*physiology
EDAT- 2005/04/16 09:00
MHDA- 2005/10/01 09:00
CRDT- 2005/04/16 09:00
PHST- 2005/04/16 09:00 [pubmed]
PHST- 2005/10/01 09:00 [medline]
PHST- 2005/04/16 09:00 [entrez]
AID - 01261.2004 [pii]
AID - 10.1152/japplphysiol.01261.2004 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 2005 Aug;99(2):707-14. doi: 
      10.1152/japplphysiol.01261.2004. Epub 2005 Apr 14.