PMID- 15836795
OWN - NLM
STAT- MEDLINE
DCOM- 20060126
LR  - 20181113
IS  - 1471-2105 (Electronic)
IS  - 1471-2105 (Linking)
VI  - 6
DP  - 2005 Apr 18
TI  - MARS: microarray analysis, retrieval, and storage system.
PG  - 101
AB  - BACKGROUND: Microarray analysis has become a widely used technique for the study 
      of gene-expression patterns on a genomic scale. As more and more laboratories are 
      adopting microarray technology, there is a need for powerful and easy to use 
      microarray databases facilitating array fabrication, labeling, hybridization, and 
      data analysis. The wealth of data generated by this high throughput approach 
      renders adequate database and analysis tools crucial for the pursuit of insights 
      into the transcriptomic behavior of cells. RESULTS: MARS (Microarray Analysis and 
      Retrieval System) provides a comprehensive MIAME supportive suite for storing, 
      retrieving, and analyzing multi color microarray data. The system comprises a 
      laboratory information management system (LIMS), a quality control management, as 
      well as a sophisticated user management system. MARS is fully integrated into an 
      analytical pipeline of microarray image analysis, normalization, gene expression 
      clustering, and mapping of gene expression data onto biological pathways. The 
      incorporation of ontologies and the use of MAGE-ML enables an export of studies 
      stored in MARS to public repositories and other databases accepting these 
      documents. CONCLUSION: We have developed an integrated system tailored to serve 
      the specific needs of microarray based research projects using a unique fusion of 
      Web based and standalone applications connected to the latest J2EE application 
      server technology. The presented system is freely available for academic and 
      non-profit institutions. More information can be found at 
      http://genome.tugraz.at.
FAU - Maurer, Michael
AU  - Maurer M
AD  - Institute for Genomics and Bioinformatics, Christian Doppler Laboratory for 
      Genomics and Bioinformatics, Graz University of Technology, Petersgasse 14, 8010 
      Graz, Austria. michael.maurer@gmail.com
FAU - Molidor, Robert
AU  - Molidor R
FAU - Sturn, Alexander
AU  - Sturn A
FAU - Hartler, Juergen
AU  - Hartler J
FAU - Hackl, Hubert
AU  - Hackl H
FAU - Stocker, Gernot
AU  - Stocker G
FAU - Prokesch, Andreas
AU  - Prokesch A
FAU - Scheideler, Marcel
AU  - Scheideler M
FAU - Trajanoski, Zlatko
AU  - Trajanoski Z
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050418
PL  - England
TA  - BMC Bioinformatics
JT  - BMC bioinformatics
JID - 100965194
SB  - IM
MH  - Algorithms
MH  - Computational Biology/*methods
MH  - Computer Graphics
MH  - Database Management Systems
MH  - Gene Expression Profiling/*methods
MH  - Genome
MH  - *Information Storage and Retrieval
MH  - Internet
MH  - Nucleic Acid Hybridization
MH  - Oligonucleotide Array Sequence Analysis/*methods
MH  - Programming Languages
MH  - *Software
MH  - Software Design
MH  - Transcription, Genetic
MH  - User-Computer Interface
PMC - PMC1090551
EDAT- 2005/04/20 09:00
MHDA- 2006/01/27 09:00
PMCR- 2005/04/18
CRDT- 2005/04/20 09:00
PHST- 2005/02/03 00:00 [received]
PHST- 2005/04/18 00:00 [accepted]
PHST- 2005/04/20 09:00 [pubmed]
PHST- 2006/01/27 09:00 [medline]
PHST- 2005/04/20 09:00 [entrez]
PHST- 2005/04/18 00:00 [pmc-release]
AID - 1471-2105-6-101 [pii]
AID - 10.1186/1471-2105-6-101 [doi]
PST - epublish
SO  - BMC Bioinformatics. 2005 Apr 18;6:101. doi: 10.1186/1471-2105-6-101.