PMID- 15853904 OWN - NLM STAT- MEDLINE DCOM- 20050919 LR - 20221207 IS - 0001-2815 (Print) IS - 0001-2815 (Linking) VI - 65 IP - 5 DP - 2005 May TI - A new HLA-A allele, HLA-A*6824, identified in three unrelated individuals. PG - 485-7 AB - A novel allele, human leukocyte antigen (HLA)-A*6824, has been identified in three unrelated individuals of northwestern European origin in a period of less than 4 months, implying that this allele may be quite common in this population. HLA-A*6824 differs from A*680102 by a single nucleotide change at position 275 in exon 2, which results in a conservative amino acid substitution from lysine to arginine in the peptide-binding groove at codon 68. FAU - Davey, S AU - Davey S AD - H&I Laboratory, National Blood Service, Colindale, London, UK. FAU - Carter, V AU - Carter V FAU - Goodman, R AU - Goodman R FAU - Day, S AU - Day S FAU - Brown, C AU - Brown C FAU - Morris, J AU - Morris J FAU - Key, T AU - Key T FAU - Bendukidze, N AU - Bendukidze N FAU - Dunn, P P J AU - Dunn PP LA - eng SI - GENBANK/AJ538185 SI - GENBANK/AJ538194 SI - GENBANK/AJ550620 SI - GENBANK/AJ550621 PT - Journal Article PL - England TA - Tissue Antigens JT - Tissue antigens JID - 0331072 RN - 0 (HLA-A Antigens) RN - 0 (HLA-A*68:24 antigen) SB - IM MH - Adult MH - Alleles MH - Amino Acid Substitution MH - England MH - Exons/genetics MH - Female MH - *Genes, MHC Class I MH - HLA-A Antigens/chemistry/*genetics/isolation & purification MH - Haplotypes/genetics MH - Humans MH - Male MH - Molecular Sequence Data MH - *Polymorphism, Single Nucleotide MH - White People/genetics EDAT- 2005/04/28 09:00 MHDA- 2005/09/20 09:00 CRDT- 2005/04/28 09:00 PHST- 2005/04/28 09:00 [pubmed] PHST- 2005/09/20 09:00 [medline] PHST- 2005/04/28 09:00 [entrez] AID - TAN399 [pii] AID - 10.1111/j.1399-0039.2005.00399.x [doi] PST - ppublish SO - Tissue Antigens. 2005 May;65(5):485-7. doi: 10.1111/j.1399-0039.2005.00399.x.