PMID- 15853905
OWN - NLM
STAT- MEDLINE
DCOM- 20050919
LR  - 20111117
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 65
IP  - 5
DP  - 2005 May
TI  - Routine HLA-B genotyping with PCR-sequence-specific oligonucleotides detects a 
      B*52 variant (B*5206).
PG  - 488-92
AB  - A new human leukocyte antigen (HLA)-B allele was found during routine typing of 
      samples for a German unrelated bone marrow donor registry, the "Aktion 
      Knochenmarkspende Bayern". After first interpretation of data of two independent 
      low-resolution sequence-specific oligonucleotide typing tests, a B*51 variant was 
      suggested. Further analysis via sequence-based typing identified the sequence as 
      new B*52 allele. This new allele officially assigned as B*5206 differs from 
      HLA-B*520102 by one nucleotide exchange in exon 2. The mutation is located at 
      nucleotide position 274, at which a cytosine is substituted by a thymine leading 
      to an amino acid change at protein position 67 from serine (TCC) to phenylalanine 
      (TTC).
FAU - Hoelsch, K
AU  - Hoelsch K
AD  - Laboratory for Medical Genetics Dr Klein, Lochhamer Strasse 29, 82152 
      Martinsried, Munich, Germany.
FAU - Lenggeler, I
AU  - Lenggeler I
FAU - Pfannes, W
AU  - Pfannes W
FAU - Knabe, H
AU  - Knabe H
FAU - Klein, H-G
AU  - Klein HG
FAU - Woelpl, A
AU  - Woelpl A
LA  - eng
SI  - GENBANK/AJ749610
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-B*52:06 antigen)
RN  - 0 (HLA-B52 Antigen)
SB  - IM
MH  - Alleles
MH  - Amino Acid Substitution
MH  - Base Sequence
MH  - *Genes, MHC Class I
MH  - Genotype
MH  - Germany
MH  - HLA-B Antigens/chemistry/*genetics/isolation & purification
MH  - HLA-B52 Antigen
MH  - Humans
MH  - Molecular Sequence Data
MH  - Polymerase Chain Reaction/methods
MH  - *Polymorphism, Single Nucleotide
MH  - Sequence Alignment
MH  - Sequence Analysis, DNA
MH  - Sequence Homology, Nucleic Acid
EDAT- 2005/04/28 09:00
MHDA- 2005/09/20 09:00
CRDT- 2005/04/28 09:00
PHST- 2005/04/28 09:00 [pubmed]
PHST- 2005/09/20 09:00 [medline]
PHST- 2005/04/28 09:00 [entrez]
AID - TAN400 [pii]
AID - 10.1111/j.1399-0039.2005.00400.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2005 May;65(5):488-92. doi: 10.1111/j.1399-0039.2005.00400.x.