PMID- 15854922
OWN - NLM
STAT- MEDLINE
DCOM- 20060814
LR  - 20220408
IS  - 1552-6259 (Electronic)
IS  - 0003-4975 (Linking)
VI  - 79
IP  - 5
DP  - 2005 May
TI  - Minimally invasive mitral valve repair in the context of Barlow's disease.
PG  - 1496-9
AB  - BACKGROUND: The aim of this study is to report our overall experience with 
      minimally invasive mitral valve repair for correction of severe mitral 
      regurgitation in the setting of Barlow's disease. METHODS: Between 1999 and 2003, 
      48 patients with bileaflet prolapse in the context of Barlow's disease underwent 
      minimally invasive mitral valve repair using the "edge-to-edge" technique. Mean 
      age was 37.9 +/- 9.1 and 58% were female. Most of the patients were in New York 
      Heart Association (NYHA) class I or II and all of them had normal left 
      ventricular ejection fraction. RESULTS: There were no conversions to sternotomy. 
      Mean cardiopulmonary bypass and aortic cross-clamp times were 77 +/- 16 minutes 
      and 56 +/- 8 minutes. No in-hospital deaths and no major postoperative 
      complications occurred. At a mean follow-up of 22.7 +/- 10.6 months, survival 
      rate and freedom from reoperation were 100%. All patients were in NYHA class I 
      and in sinus rhythm. No residual mitral regurgitation was detected at 
      echocardiography in 33 (68.7%) patients and mild insufficiency was found in 15 
      (31.2%). The degree of satisfaction in terms of cosmesis and postoperative pain 
      was very high and 73% of the patients were back to work and to normal activity in 
      4 weeks. CONCLUSIONS: Mitral insufficiency due to Barlow's disease can be 
      effectively corrected through a minimally invasive approach by using the 
      "edge-to-edge" technique. In our opinion, the excellent midterm results and the 
      high degree of patients satisfaction certainly justify the adoption of this 
      strategy in a selected group of young and active people.
FAU - Lapenna, Elisabetta
AU  - Lapenna E
AD  - Department of Cardiac Surgery, San Raffaele University Hospital, Milan, Italy. 
      lapenna.elisabetta@hsr.it
FAU - Torracca, Lucia
AU  - Torracca L
FAU - De Bonis, Michele
AU  - De Bonis M
FAU - La Canna, Giovanni
AU  - La Canna G
FAU - Crescenzi, Giuseppe
AU  - Crescenzi G
FAU - Alfieri, Ottavio
AU  - Alfieri O
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Minimally Invasive Surgical Procedures
MH  - Mitral Valve/*surgery
MH  - Mitral Valve Insufficiency/*surgery
MH  - Mitral Valve Prolapse/*surgery
MH  - Monitoring, Intraoperative
MH  - Retrospective Studies
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2005/04/28 09:00
MHDA- 2006/08/15 09:00
CRDT- 2005/04/28 09:00
PHST- 2004/10/20 00:00 [accepted]
PHST- 2005/04/28 09:00 [pubmed]
PHST- 2006/08/15 09:00 [medline]
PHST- 2005/04/28 09:00 [entrez]
AID - S0003-4975(04)02134-4 [pii]
AID - 10.1016/j.athoracsur.2004.10.032 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 2005 May;79(5):1496-9. doi: 10.1016/j.athoracsur.2004.10.032.