PMID- 15855191
OWN - NLM
STAT- MEDLINE
DCOM- 20060208
LR  - 20061115
IS  - 0195-668X (Print)
IS  - 0195-668X (Linking)
VI  - 26
IP  - 17
DP  - 2005 Sep
TI  - Dendritic cells in atherosclerosis: current status of the problem and clinical 
      relevance.
PG  - 1700-4
AB  - Dendritic cells (DCs) are the most potent antigen-presenting cells. DCs were 
      identified in arteries in 1995 and, since then, further knowledge has been gained 
      indicating the importance of DCs in atherosclerosis. Vascular DCs have been shown 
      to become activated from a very early stage of atherosclerosis. Some DCs cluster 
      with T cells directly within atherosclerotic lesions, while others migrate to 
      lymphoid organs to activate T cells. Dyslipidaemia systemically alters DC 
      function and recent findings suggest that DCs play a role in plaque 
      destabilization. This review summarizes the current status of the problem.
FAU - Bobryshev, Yuri V
AU  - Bobryshev YV
AD  - Surgical Professorial Unit, Level 5, DeLacy Building, St Vincent's Hospital 
      Sydney, University of New South Wales, Darlinghurst, New South Wales 2010, 
      Australia. y.bobryshev@unsw.edu.au
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20050426
PL  - England
TA  - Eur Heart J
JT  - European heart journal
JID - 8006263
SB  - IM
CIN - Eur Heart J. 2006 Jan;27(1):116; author reply 116-7. PMID: 16267069
MH  - Atherosclerosis/*immunology/therapy
MH  - Dendritic Cells/*immunology
MH  - Endothelium, Vascular/immunology
MH  - Humans
MH  - Immunity, Cellular
RF  - 59
EDAT- 2005/04/28 09:00
MHDA- 2006/02/09 09:00
CRDT- 2005/04/28 09:00
PHST- 2005/04/28 09:00 [pubmed]
PHST- 2006/02/09 09:00 [medline]
PHST- 2005/04/28 09:00 [entrez]
AID - ehi282 [pii]
AID - 10.1093/eurheartj/ehi282 [doi]
PST - ppublish
SO  - Eur Heart J. 2005 Sep;26(17):1700-4. doi: 10.1093/eurheartj/ehi282. Epub 2005 Apr 
      26.