PMID- 15861791
OWN - NLM
STAT- MEDLINE
DCOM- 20050929
LR  - 20190720
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1070
IP  - 1-2
DP  - 2005 Apr 8
TI  - Comprehensive two-dimensional liquid chromatography and hyphenated liquid 
      chromatography to study the degradation of poly(bisphenol A)carbonate.
PG  - 79-87
AB  - Size exclusion chromatography (SEC), gradient polymer elution chromatography 
      (GPEC) and liquid chromatography at critical conditions (LC-CC) have been 
      developed and applied to observe chemical changes in poly(bisphenol A)carbonate 
      (PC) due to hydrolytic degradation. Especially LC-CC appeared to be very 
      successful to observe differences in functionality of PC as result of hydrolytic 
      degradation. Observed differences due to degradation could be identified by 
      (semi) on-line coupling to matrix assisted laser desorption-ionization 
      time-of-flight mass spectrometry (MALDI-TOF-MS). The differences in functionality 
      could be attributed to the formation of different end-groups, i.e. OH end-groups. 
      In addition, comprehensive two-dimensional liquid chromatography (2D-LC) has been 
      applied successfully to study the hydrolytic degradation of PC. LC-CC x SEC 
      showed that the formation of PC with different end-groups occurred over the whole 
      molecular mass range. This information could not be obtained with the separate 
      liquid chromatographic techniques, thereby illustrating the added value of 2D-LC.
FAU - Coulier, L
AU  - Coulier L
AD  - Packaging Research and Polymer Analysis Group, Analytical Sciences Department, 
      TNO Quality of Life, Utrechtseweg 48, 3704 HE Zeist, The Netherlands. 
      coulier@voeding.tno.nl
FAU - Kaal, E R
AU  - Kaal ER
FAU - Hankemeier, Th
AU  - Hankemeier T
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Benzhydryl Compounds)
RN  - 0 (Polymers)
RN  - 25037-45-0 (bisphenol-A-polycarbonate)
SB  - IM
MH  - Benzhydryl Compounds
MH  - Chromatography, Gel/*methods
MH  - Polymers/*chemistry
MH  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
MH  - Spectrophotometry, Ultraviolet
EDAT- 2005/05/03 09:00
MHDA- 2005/09/30 09:00
CRDT- 2005/05/03 09:00
PHST- 2005/05/03 09:00 [pubmed]
PHST- 2005/09/30 09:00 [medline]
PHST- 2005/05/03 09:00 [entrez]
AID - S0021-9673(05)00327-4 [pii]
AID - 10.1016/j.chroma.2005.02.067 [doi]
PST - ppublish
SO  - J Chromatogr A. 2005 Apr 8;1070(1-2):79-87. doi: 10.1016/j.chroma.2005.02.067.