PMID- 15875060
OWN - NLM
STAT- MEDLINE
DCOM- 20050907
LR  - 20071115
IS  - 0955-9930 (Print)
IS  - 0955-9930 (Linking)
VI  - 17
IP  - 4
DP  - 2005 Jul-Aug
TI  - Erectile dysfunction and HTLV-I infection: a silent problem.
PG  - 364-9
AB  - The human T-lymphotropic virus type I (HTLV-I) is a retrovirus associated with a 
      chronic myelopathy known as HTLV-I-Associated Myelopathy or Tropical Spastic 
      Paraparesis (HAM/TSP). The main objective was to assess the frequency of erectile 
      dysfunction (ED) in HTLV-I-infected individuals from Salvador and other cities 
      from Bahia, Brazil, as well as to verify if sexual dysfunction correlates with 
      urinary symptoms and overall neurological impairment. From January 2001 to April 
      2004, 218 HTLV-I carriers (111 male and 107 female subjects) had complete 
      clinical, neurological, and urological evaluation. They were assessed using 
      standardized questionnaires to determine urinary complaints (Urinary Distress 
      Inventory) and ED (Brief Male Sexual Function Inventory). Neurological impairment 
      was established by Expanded Disability Status Scale (EDSS) from 0 to 10. HAM/TSP 
      was considered as EDSS> or =2. A total of 17 males had clinically defined HAM/TSP 
      (group 1). From the 94 HTLV-I-infected males, 62 were selected (group 2) and 
      paired by age with patients in group 1. A total of 79 individuals were selected 
      for this study. The age ranged from 35 to 81 y (mean=47.9+/-9.65). The percentage 
      of ED in the studied population was 40.5%. In the HAM/TSP group, ED frequency was 
      88.2%. The associations among sexual dissatisfaction, erectile dysfunction, 
      urinary symptoms (frequency, nocturia, and urgency) and EDSS> or =2 were 
      statistically significant. In HAM/TSP, there is a slow and progressive 
      degeneration of the lateral funiculus of the spinal cord. HTLV-I-infected 
      individuals present a high frequency of ED and it is closely associated to 
      urinary symptoms and the overall neurological picture. The HTLV-I carriers 
      already had prominent compromise of the sexual activity.
FAU - Castro, N
AU  - Castro N
AD  - Servico de Imunologia, Hospital Universitario Professor Edgard Santos, Salvador, 
      Bahia, Brazil. neviton_castro@aol.com.br
FAU - Oliveira, P
AU  - Oliveira P
FAU - Freitas, D
AU  - Freitas D
FAU - Rodrigues, W
AU  - Rodrigues W
FAU - Muniz, A
AU  - Muniz A
FAU - Carvalho, E
AU  - Carvalho E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Int J Impot Res
JT  - International journal of impotence research
JID - 9007383
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Brazil/epidemiology
MH  - Erectile Dysfunction/*epidemiology/*virology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Outpatients/statistics & numerical data
MH  - Paraparesis, Tropical Spastic/*epidemiology
MH  - Prevalence
MH  - Spinal Cord Diseases/epidemiology/virology
MH  - Urination Disorders/epidemiology/virology
EDAT- 2005/05/06 09:00
MHDA- 2005/09/08 09:00
CRDT- 2005/05/06 09:00
PHST- 2005/05/06 09:00 [pubmed]
PHST- 2005/09/08 09:00 [medline]
PHST- 2005/05/06 09:00 [entrez]
AID - 3901335 [pii]
AID - 10.1038/sj.ijir.3901335 [doi]
PST - ppublish
SO  - Int J Impot Res. 2005 Jul-Aug;17(4):364-9. doi: 10.1038/sj.ijir.3901335.