PMID- 15878581 OWN - NLM STAT- MEDLINE DCOM- 20050725 LR - 20050509 IS - 1353-8020 (Print) IS - 1353-8020 (Linking) VI - 11 IP - 4 DP - 2005 Jun TI - Visual event-related potentials under different interstimulus intervals in Parkinson's disease: relation to motor disability, WAIS-R, and regional cerebral blood flow. PG - 209-19 AB - We have introduced S1-S2 paradigm (task S) as well as oddball paradigm (task O) visual event-related potentials (ERPs) under different interstimulus intervals (ISIs) in Parkinson's disease (PD). ERP measurements were correlated with motor disability, WAIS-R, and regional cerebral blood flow (rCBF). The 'group' influence was characterized by longer latency for P300, N200, and reaction time and decreased P300 amplitude in PD. Both P300 latency and reaction time during task O showed significantly longer latency in longer ISI condition. Our results revealed 'ISI' influence on ERPs during task S and significant correlation between ERPs and rCBF in task S. FAU - Li, Mei AU - Li M AD - Department of Neurology, Graduate School of Medicine, Yokohama City University, 3-9 Fukuura, Yokohama 236-0004, Japan. FAU - Kuroiwa, Yoshiyuki AU - Kuroiwa Y FAU - Wang, Lihong AU - Wang L FAU - Kamitani, Toshiaki AU - Kamitani T FAU - Omoto, Shu AU - Omoto S FAU - Hayashi, Eiko AU - Hayashi E FAU - Takahashi, Tatsuya AU - Takahashi T FAU - Suzuki, Yume AU - Suzuki Y FAU - Koyano, Shigeru AU - Koyano S FAU - Ikegami, Tadashi AU - Ikegami T FAU - Matsubara, Sho AU - Matsubara S LA - eng PT - Journal Article DEP - 20050420 PL - England TA - Parkinsonism Relat Disord JT - Parkinsonism & related disorders JID - 9513583 SB - IM MH - Aged MH - Analysis of Variance MH - *Cerebrovascular Circulation MH - Cognition Disorders/diagnosis/physiopathology MH - *Disability Evaluation MH - Electroencephalography MH - Event-Related Potentials, P300 MH - *Evoked Potentials, Visual MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Motor Activity MH - Parkinson Disease/diagnosis/*physiopathology MH - Reaction Time EDAT- 2005/05/10 09:00 MHDA- 2005/07/26 09:00 CRDT- 2005/05/10 09:00 PHST- 2004/09/21 00:00 [received] PHST- 2004/11/16 00:00 [revised] PHST- 2004/11/17 00:00 [accepted] PHST- 2005/05/10 09:00 [pubmed] PHST- 2005/07/26 09:00 [medline] PHST- 2005/05/10 09:00 [entrez] AID - S1353-8020(04)00198-1 [pii] AID - 10.1016/j.parkreldis.2004.11.004 [doi] PST - ppublish SO - Parkinsonism Relat Disord. 2005 Jun;11(4):209-19. doi: 10.1016/j.parkreldis.2004.11.004. Epub 2005 Apr 20.