PMID- 15891042 OWN - NLM STAT- MEDLINE DCOM- 20060829 LR - 20061115 IS - 0077-8923 (Print) IS - 0077-8923 (Linking) VI - 1040 DP - 2005 Apr TI - Cloning and expression of guanylin-like peptides in teleost fish. PG - 277-80 AB - Homologues of the guanylin peptide family are expressed in teleost fish. Using the eel as a model euryhaline species, cDNAs for three peptides, guanylin, uroguanylin, and renoguanylin, were cloned and found to be expressed within both renal and intestinal epithelia. Seawater (SW) acclimation resulted in upregulation of uroguanylin mRNA expression in the intestinal epithelia of both immature "yellow" and sexually mature "silver" eels. SW acclimation also resulted in an increase in guanylin mRNA in silver eel intestine, whereas there was no change in renoguanylin mRNA expression under any condition. No changes in expression were found in the kidney following SW acclimation. FAU - Cramb, Gordon AU - Cramb G AD - School of Biology, Bute Medical Buildings, University of Saint Andrews, UK. gc@st-and.ac.uk FAU - Martinez, Anne-Sophie AU - Martinez AS FAU - McWilliam, Iain S AU - McWilliam IS FAU - Wilson, Gillian D AU - Wilson GD LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - Ann N Y Acad Sci JT - Annals of the New York Academy of Sciences JID - 7506858 RN - 0 (Gastrointestinal Hormones) RN - 0 (Natriuretic Peptides) RN - 140653-38-9 (guanylin) SB - IM MH - Amino Acid Sequence MH - Animals MH - *Cloning, Molecular/methods MH - Eels/genetics/*metabolism MH - Gastrointestinal Hormones/*biosynthesis/genetics MH - Gene Expression Regulation/physiology MH - Molecular Sequence Data MH - Natriuretic Peptides/*biosynthesis/genetics EDAT- 2005/05/14 09:00 MHDA- 2006/08/30 09:00 CRDT- 2005/05/14 09:00 PHST- 2005/05/14 09:00 [pubmed] PHST- 2006/08/30 09:00 [medline] PHST- 2005/05/14 09:00 [entrez] AID - 1040/1/277 [pii] AID - 10.1196/annals.1327.042 [doi] PST - ppublish SO - Ann N Y Acad Sci. 2005 Apr;1040:277-80. doi: 10.1196/annals.1327.042.