PMID- 15893358
OWN - NLM
STAT- MEDLINE
DCOM- 20060103
LR  - 20131121
IS  - 0045-6535 (Print)
IS  - 0045-6535 (Linking)
VI  - 61
IP  - 9
DP  - 2005 Dec
TI  - Bioconcentration factor of relatively low concentrations of chlorophenols in 
      Japanese medaka.
PG  - 1299-304
AB  - Bioconcentration factors (BCF) for pentachlorophenol (PCP) and 2,4-dichlorophenol 
      (2,4-DCP) in Japanese medaka (Oryzias latipes) were determined at five different 
      concentrations of the chemicals, between 0.1 and 10 microg/l (PCP), 0.3 and 30 
      microg/l (2,4-DCP), in the ambient water. Medaka were exposed to each chemicals 
      in a continuous-flow system during the embryonic development period and 60 days 
      after hatching from eggs collected in the laboratory. Both the exposure time and 
      the aqueous concentrations are much more realistic and closer to natural aquatic 
      environments than those used in conventional BCF studies. The BCF values of PCP 
      were from (4.9+/-2.8)x10(3) at the aqueous concentration of 0.074+/-0.028 
      microg/l to (2.1+/-1.4)x10(3) at 9.70+/-0.56 microg/l. The BCF value of 2,4-DCP 
      were from (3.4+/-3.0)x10(2) at 0.235+/-0.060 microg/l to 92+/-27 at 27.3+/-1.6 
      microg/l. Generally, BCF values increased as the aqueous concentrations of PCP or 
      2,4-DCP decreased. This finding suggests that a relatively low and realistic 
      aqueous concentration of these compounds is necessary to more accurately 
      determine their BCF values in natural aquatic environments. Conventional BCF 
      experiments at higher aqueous concentrations may underestimate the BCF values.
FAU - Kondo, Takuya
AU  - Kondo T
AD  - National Inst. for Environ. Studies, 16-2 Onogawa, Tsukuba City, Ibaraki 
      305-8506, Japan.
FAU - Yamamoto, Hiroshi
AU  - Yamamoto H
FAU - Tatarazako, Norihisa
AU  - Tatarazako N
FAU - Kawabe, Kiyoshi
AU  - Kawabe K
FAU - Koshio, Masaaki
AU  - Koshio M
FAU - Hirai, Narisato
AU  - Hirai N
FAU - Morita, Masatoshi
AU  - Morita M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Chlorophenols)
RN  - 0 (Water Pollutants, Chemical)
RN  - D9BSU0SE4T (Pentachlorophenol)
RN  - R669TG1950 (2,4-dichlorophenol)
SB  - IM
MH  - Animals
MH  - Chlorophenols/analysis/*pharmacokinetics
MH  - Environmental Monitoring
MH  - Japan
MH  - *Oryzias
MH  - Pentachlorophenol/analysis/*pharmacokinetics
MH  - Tissue Distribution
MH  - Water Pollutants, Chemical/analysis/*pharmacokinetics
EDAT- 2005/05/17 09:00
MHDA- 2006/01/04 09:00
CRDT- 2005/05/17 09:00
PHST- 2004/09/22 00:00 [received]
PHST- 2005/02/18 00:00 [revised]
PHST- 2005/03/23 00:00 [accepted]
PHST- 2005/05/17 09:00 [pubmed]
PHST- 2006/01/04 09:00 [medline]
PHST- 2005/05/17 09:00 [entrez]
AID - S0045-6535(05)00473-X [pii]
AID - 10.1016/j.chemosphere.2005.03.058 [doi]
PST - ppublish
SO  - Chemosphere. 2005 Dec;61(9):1299-304. doi: 10.1016/j.chemosphere.2005.03.058.