PMID- 15895406 OWN - NLM STAT- MEDLINE DCOM- 20051110 LR - 20101118 IS - 1522-1946 (Print) IS - 1522-1946 (Linking) VI - 65 IP - 2 DP - 2005 Jun TI - Left ventricular unloading and concomitant total cardiac output increase by the use of percutaneous Impella Recover LP 2.5 assist device during high-risk coronary intervention. PG - 263-7 AB - A number of techniques have been proposed for circulatory support during high-risk percutaneous coronary interventions (PCI), but no single approach has achieved wide acceptance so far. We report on a patient with severe left ventricular (LV) impairment who underwent a PCI with the use of a new left ventricular assist device, the Impella Recover LP 2.5 system. The effects on global cardiac output were determined by thermodilution (TD) and LV pressure-volume loops obtained by conductance catheter. The activation of the pump resulted in a rapid and sustained unloading effect of the LV. At the same time, the continuous expulsion of blood into ascending aorta throughout the cardiac cycle produced by the pump resulted in an increase of systemic overall CO, measured by the TD technique, of 1.43 L/min. The procedure was uncomplicated and the patient remained uneventful at follow-up. Our single experience gives new input for future trials to assess the effect of the Impella Recover LP 2.5 assist device on outcome in this subset of patients. CI - Copyright 2005 Wiley-Liss, Inc FAU - Valgimigli, Marco AU - Valgimigli M AD - Department of Interventional Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands. FAU - Steendijk, Paul AU - Steendijk P FAU - Sianos, George AU - Sianos G FAU - Onderwater, Emile AU - Onderwater E FAU - Serruys, Patrick W AU - Serruys PW LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Catheter Cardiovasc Interv JT - Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions JID - 100884139 SB - IM MH - *Angioplasty, Balloon, Coronary MH - Cardiac Output/physiology MH - *Heart-Assist Devices MH - Humans MH - Male MH - Middle Aged MH - Treatment Outcome MH - Ventricular Dysfunction, Left/diagnosis/physiopathology/*therapy MH - Ventricular Pressure/physiology EDAT- 2005/05/17 09:00 MHDA- 2005/11/11 09:00 CRDT- 2005/05/17 09:00 PHST- 2005/05/17 09:00 [pubmed] PHST- 2005/11/11 09:00 [medline] PHST- 2005/05/17 09:00 [entrez] AID - 10.1002/ccd.20380 [doi] PST - ppublish SO - Catheter Cardiovasc Interv. 2005 Jun;65(2):263-7. doi: 10.1002/ccd.20380.