PMID- 15900642
OWN - NLM
STAT- MEDLINE
DCOM- 20050801
LR  - 20191109
IS  - 0172-4622 (Print)
IS  - 0172-4622 (Linking)
VI  - 26
IP  - 4
DP  - 2005 May
TI  - Fluids containing a highly branched cyclic dextrin influence the gastric emptying 
      rate.
PG  - 314-9
AB  - The rates of gastric emptying for highly branched cyclic dextrin (HBCD) and other 
      carbohydrate (CHO) solutions were examined using ultrasonograph techniques. Ten 
      healthy volunteers ingested water, physiological saline, or solutions containing 
      various CHO, such as HBCD, glucose, maltose, sucrose, and commercially available 
      dextrin. After a subject drank one of the solutions, the relaxed cross-sectional 
      area of the pylorus antrum was measured at rest by real-time ultrasonography. The 
      time required for gastric emptying was correlated with the relaxed 
      cross-sectional area of the pylorus antrum. Among all of the solutions tested, 
      physiological saline was transferred fastest from the stomach to the small 
      intestine. For solutions of the same CHO, 5 % solution was transferred faster 
      than 10 % solution. For CHO solutions other than HBCD, a low osmotic pressure was 
      associated with rapid transfer from the stomach. The gastric emptying time (GET) 
      of HBCD solution increased with an increase in its concentration. A shorter GET 
      was observed for the CHO solutions at 59 to 160 mOsm regardless of their 
      concentration. A sports drink based on 10 % HBCD adjusted to 150 mOsm by the 
      addition of various minerals, vitamins, and organic acids was evacuated 
      significantly (p < 0.05) faster than a 10 % HBCD solution or a sports drink based 
      on 10 % commercially available dextrin (DE16), which has a higher osmotic 
      pressure (269 mOsm). Our results suggest that a shorter GET could be achieved 
      with CHO solutions with osmotic pressures of 59 - 160 mOsm. Therefore, a sports 
      drink based on 10 % HBCD adjusted to 150 mOsm by the addition of minerals, 
      vitamins, and organic acids could supply adequate quantities of CHO, fluid, and 
      minerals simultaneously in a short time, without increasing GET.
FAU - Takii, H
AU  - Takii H
AD  - Biochemical Research Laboratory, Ezaki Glico Co., Ltd., Osaka, Japan. 
      takii-hiroshi@glico.co.jp
FAU - Takii Nagao, Y
AU  - Takii Nagao Y
FAU - Kometani, T
AU  - Kometani T
FAU - Nishimura, T
AU  - Nishimura T
FAU - Nakae, T
AU  - Nakae T
FAU - Kuriki, T
AU  - Kuriki T
FAU - Fushiki, T
AU  - Fushiki T
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PL  - Germany
TA  - Int J Sports Med
JT  - International journal of sports medicine
JID - 8008349
RN  - 0 (Dextrins)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Solutions)
RN  - 059QF0KO0R (Water)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Administration, Oral
MH  - Adult
MH  - *Beverages
MH  - Dextrins/*administration & dosage
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Female
MH  - Gastric Emptying/*drug effects
MH  - Glucose/administration & dosage
MH  - Humans
MH  - Male
MH  - Osmotic Pressure
MH  - Pylorus/diagnostic imaging
MH  - Rest/physiology
MH  - Solutions
MH  - Ultrasonography
MH  - Water/administration & dosage
EDAT- 2005/05/20 09:00
MHDA- 2005/08/02 09:00
CRDT- 2005/05/20 09:00
PHST- 2005/05/20 09:00 [pubmed]
PHST- 2005/08/02 09:00 [medline]
PHST- 2005/05/20 09:00 [entrez]
AID - 10.1055/s-2004-820999 [doi]
PST - ppublish
SO  - Int J Sports Med. 2005 May;26(4):314-9. doi: 10.1055/s-2004-820999.