PMID- 15902986
OWN - NLM
STAT- MEDLINE
DCOM- 20050725
LR  - 20191109
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 15
IP  - 1
DP  - 2005 Feb
TI  - The effects of medium-chain triacylglycerol and carbohydrate ingestion on 
      ultra-endurance exercise performance.
PG  - 15-27
AB  - The aims of the study were to determine if medium-chain triacylglycerol (MCT), 
      ingested in combination with carbohydrate (CHO), would alter substrate metabolism 
      and improve simulated competitive ultra-endurance cycling performance. Eight 
      endurance-trained cyclists took part in this randomized, single-blind crossover 
      study. On two separate occasions, subjects cycled for 270 min at 50% of peak 
      power output, interspersed with four 75 kJ sprints at 60 min intervals, followed 
      immediately by a 200 kJ time-trial. One hour prior to the exercise trials, 
      subjects ingested either 75 g of CHO or 32 g of MCT, and then ingested 200 mL of 
      a 10% CHO (wt/vol) solution or a 4.3% MCT + 10% CHO (wt/vol) solution every 20 
      min during the CHO and MCT trials, respectively. During the constant-load phases 
      of the 270 min exercise trial, VO2. RER, and heart rate were measured at 30 min 
      intervals and gastrointestinal (GI) symptoms were recorded. There was no 
      difference in VO2 or RER between the MCT and CHO trials (P = 0.40). Hourly sprint 
      (P = 0.03 for trial x time interaction) and time-trial times (14:30 +/- 0.58 vs. 
      12:36 +/- 1:6, respectively, P < 0.001) were slower in the MCT than the CHO 
      trial. Half the subjects experienced GI symptoms with MCT ingestion. In 
      conclusion, MCTs ingested prior to exercise and co-ingested with CHO during 
      exercise did not alter substrate metabolism and significantly compromised sprint 
      performance during prolonged ultra-endurance cycling exercise.
FAU - Goedecke, Julia H
AU  - Goedecke JH
AD  - Medical Research Council Research Unit for Exercise Science and Sports Medicine, 
      University of Cape Town, Cape Town 7725, South Africa.
FAU - Clark, Virginia R
AU  - Clark VR
FAU - Noakes, Timothy D
AU  - Noakes TD
FAU - Lambert, Estelle V
AU  - Lambert EV
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Triglycerides)
SB  - IM
MH  - Adult
MH  - Basal Metabolism/physiology
MH  - Bicycling/physiology
MH  - Cross-Over Studies
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Energy Metabolism/*drug effects/physiology
MH  - Gastrointestinal Tract/drug effects
MH  - Heart Rate/physiology
MH  - Humans
MH  - Male
MH  - Oxidation-Reduction
MH  - Oxygen Consumption
MH  - Physical Endurance/*drug effects/physiology
MH  - Pulmonary Gas Exchange
MH  - Single-Blind Method
MH  - Time Factors
MH  - Triglycerides/*administration & dosage/adverse effects/chemistry
EDAT- 2005/05/21 09:00
MHDA- 2005/07/26 09:00
CRDT- 2005/05/21 09:00
PHST- 2005/05/21 09:00 [pubmed]
PHST- 2005/07/26 09:00 [medline]
PHST- 2005/05/21 09:00 [entrez]
AID - 10.1123/ijsnem.15.1.15 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2005 Feb;15(1):15-27. doi: 10.1123/ijsnem.15.1.15.