PMID- 15919222 OWN - NLM STAT- MEDLINE DCOM- 20050921 LR - 20161020 IS - 1286-4579 (Print) IS - 1286-4579 (Linking) VI - 7 IP - 7-8 DP - 2005 Jun TI - Manipulating dendritic cells to induce regulatory T cells. PG - 1033-9 AB - Dendritic cells (DCs) induce and regulate T-cell responses, and tolerogenic DCs can promote the development of regulatory T cells with suppressive activity. The possibility of manipulating DCs using different pharmacological or biological agents, enabling them to exert tolerogenic activities, could be exploited to better control a variety of chronic inflammatory conditions, from autoimmune diseases to allograft rejection. FAU - Penna, G AU - Penna G AD - BioXell, Milan, Italy. FAU - Giarratana, N AU - Giarratana N FAU - Amuchastegui, S AU - Amuchastegui S FAU - Mariani, R AU - Mariani R FAU - Daniel, K C AU - Daniel KC FAU - Adorini, L AU - Adorini L LA - eng PT - Journal Article PT - Review DEP - 20050426 PL - France TA - Microbes Infect JT - Microbes and infection JID - 100883508 RN - 0 (Immunosuppressive Agents) RN - 0 (Receptors, Calcitriol) RN - 0 (Receptors, Cell Surface) SB - IM MH - Animals MH - Autoimmune Diseases/immunology MH - Dendritic Cells/drug effects/*physiology MH - Graft Rejection/immunology MH - Humans MH - Immunosuppressive Agents/pharmacology MH - Lymphocyte Activation MH - Receptors, Calcitriol/agonists MH - Receptors, Cell Surface/metabolism MH - T-Lymphocytes/*physiology RF - 50 EDAT- 2005/05/28 09:00 MHDA- 2005/09/22 09:00 CRDT- 2005/05/28 09:00 PHST- 2005/03/23 00:00 [received] PHST- 2005/03/25 00:00 [accepted] PHST- 2005/05/28 09:00 [pubmed] PHST- 2005/09/22 09:00 [medline] PHST- 2005/05/28 09:00 [entrez] AID - S1286-4579(05)00115-2 [pii] AID - 10.1016/j.micinf.2005.03.025 [doi] PST - ppublish SO - Microbes Infect. 2005 Jun;7(7-8):1033-9. doi: 10.1016/j.micinf.2005.03.025. Epub 2005 Apr 26.