PMID- 15929900
OWN - NLM
STAT- MEDLINE
DCOM- 20051202
LR  - 20181113
IS  - 0091-6765 (Print)
IS  - 1552-9924 (Electronic)
IS  - 0091-6765 (Linking)
VI  - 113
IP  - 6
DP  - 2005 Jun
TI  - Hospitalization rates for coronary heart disease in relation to residence near 
      areas contaminated with persistent organic pollutants and other pollutants.
PG  - 756-61
AB  - Exposure to environmental pollutants may contribute to the development of 
      coronary heart disease (CHD). We determined the ZIP codes containing or abutting 
      each of the approximately 900 hazardous waste sites in New York and identified 
      the major contaminants in each. Three categories of ZIP codes were then 
      distinguished: those containing or abutting sites contaminated with persistent 
      organic pollutants (POPs), those containing only other types of wastes ("other 
      waste"), and those not containing any identified hazardous waste site ("clean"). 
      Effects of residence in each of these ZIP codes on CHD and acute myocardial 
      infarction (AMI) hospital discharge rates were assessed with a negative binomial 
      model, adjusting for age, sex, race, income, and health insurance coverage. 
      Patients living in ZIP codes contaminated with POPs had a statistically 
      significant 15.0% elevation in CHD hospital discharge rates and a 20.0% elevation 
      in AMI discharge rates compared with clean ZIP codes. In neither of the 
      comparisons were rates in other-waste sites significantly greater than in clean 
      sites. In a subset of POP ZIP codes along the Hudson River, where average income 
      is higher and there is less smoking, better diet, and more exercise, the rate of 
      hospitalization for CHD was 35.8% greater and for AMI 39.1% greater than in clean 
      sites. Although the cross-sectional design of the study prevents definite 
      conclusions on causal inference, the results indirectly support the hypothesis 
      that living near a POP-contaminated site constitutes a risk of exposure and of 
      development of CHD and AMI.
FAU - Sergeev, Alexander V
AU  - Sergeev AV
AD  - Institute for Health and the Environment, University at Albany, Rensselaer, New 
      York 12144-3456, USA.
FAU - Carpenter, David O
AU  - Carpenter DO
LA  - eng
GR  - TW00636/TW/FIC NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Environ Health Perspect
JT  - Environmental health perspectives
JID - 0330411
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hazardous Waste)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Coronary Disease/*epidemiology/etiology
MH  - Cross-Sectional Studies
MH  - *Environmental Exposure
MH  - Environmental Pollutants/*toxicity
MH  - Female
MH  - *Hazardous Waste
MH  - Hospitalization
MH  - Housing
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*epidemiology/etiology
MH  - New York/epidemiology
PMC - PMC1257602
EDAT- 2005/06/03 09:00
MHDA- 2005/12/13 09:00
PMCR- 2005/06/01
CRDT- 2005/06/03 09:00
PHST- 2005/06/03 09:00 [pubmed]
PHST- 2005/12/13 09:00 [medline]
PHST- 2005/06/03 09:00 [entrez]
PHST- 2005/06/01 00:00 [pmc-release]
AID - ehp0113-000756 [pii]
AID - 10.1289/ehp.7595 [doi]
PST - ppublish
SO  - Environ Health Perspect. 2005 Jun;113(6):756-61. doi: 10.1289/ehp.7595.