PMID- 15930618
OWN - NLM
STAT- MEDLINE
DCOM- 20050818
LR  - 20220129
IS  - 0907-4449 (Print)
IS  - 0907-4449 (Linking)
VI  - 61
IP  - Pt 6
DP  - 2005 Jun
TI  - HalX: an open-source LIMS (Laboratory Information Management System) for small- 
      to large-scale laboratories.
PG  - 671-8
AB  - Structural genomics aims at the establishment of a universal protein-fold 
      dictionary through systematic structure determination either by NMR or X-ray 
      crystallography. In order to catch up with the explosive amount of protein 
      sequence data, the structural biology laboratories are spurred to increase the 
      speed of the structure-determination process. To achieve this goal, 
      high-throughput robotic approaches are increasingly used in all the steps leading 
      from cloning to data collection and even structure interpretation is becoming 
      more and more automatic. The progress made in these areas has begun to have a 
      significant impact on the more 'classical' structural biology laboratories, 
      dramatically increasing the number of individual experiments. This automation 
      creates the need for efficient data management. Here, a new piece of software, 
      HalX, designed as an 'electronic lab book' that aims at (i) storage and (ii) easy 
      access and use of all experimental data is presented. This should lead to much 
      improved management and tracking of structural genomics experimental data.
FAU - Prilusky, Jaime
AU  - Prilusky J
AD  - Israel Structural Proteomics Center, Weizmann Institute of Science, Rehovot 
      76100, Israel.
FAU - Oueillet, Eric
AU  - Oueillet E
FAU - Ulryck, Nathalie
AU  - Ulryck N
FAU - Pajon, Anne
AU  - Pajon A
FAU - Bernauer, Julie
AU  - Bernauer J
FAU - Krimm, Isabelle
AU  - Krimm I
FAU - Quevillon-Cheruel, Sophie
AU  - Quevillon-Cheruel S
FAU - Leulliot, Nicolas
AU  - Leulliot N
FAU - Graille, Marc
AU  - Graille M
FAU - Liger, Dominique
AU  - Liger D
FAU - Tresaugues, Lionel
AU  - Tresaugues L
FAU - Sussman, Joel L
AU  - Sussman JL
FAU - Janin, Joel
AU  - Janin J
FAU - van Tilbeurgh, Herman
AU  - van Tilbeurgh H
FAU - Poupon, Anne
AU  - Poupon A
LA  - eng
GR  - BB/C512110/1/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - BB/C512145/1/BB_/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050526
PL  - United States
TA  - Acta Crystallogr D Biol Crystallogr
JT  - Acta crystallographica. Section D, Biological crystallography
JID - 9305878
SB  - IM
MH  - Crystallography, X-Ray/methods
MH  - *Databases, Protein
MH  - *Software
EDAT- 2005/06/03 09:00
MHDA- 2005/08/19 09:00
CRDT- 2005/06/03 09:00
PHST- 2004/07/22 00:00 [received]
PHST- 2005/01/13 00:00 [accepted]
PHST- 2005/06/03 09:00 [pubmed]
PHST- 2005/08/19 09:00 [medline]
PHST- 2005/06/03 09:00 [entrez]
AID - S0907444905001290 [pii]
AID - 10.1107/S0907444905001290 [doi]
PST - ppublish
SO  - Acta Crystallogr D Biol Crystallogr. 2005 Jun;61(Pt 6):671-8. doi: 
      10.1107/S0907444905001290. Epub 2005 May 26.