PMID- 15936784
OWN - NLM
STAT- MEDLINE
DCOM- 20051115
LR  - 20220317
IS  - 0028-3932 (Print)
IS  - 0028-3932 (Linking)
VI  - 43
IP  - 10
DP  - 2005
TI  - Making sense of another mind: the role of the right temporo-parietal junction.
PG  - 1391-9
AB  - Human adults conceive of one another as beings with minds, and attribute to one 
      another mental states like perceptions, desires and beliefs. That is, we 
      understand other people using a 'Theory of Mind'. The current study investigated 
      the contributions of four brain regions to Theory of Mind reasoning. The right 
      temporo-parietal junction (RTPJ) was recruited selectively for the attribution of 
      mental states, and not for other socially relevant facts about a person, and the 
      response of the RTPJ was modulated by the congruence or incongruence of multiple 
      relevant facts about the target's mind. None of the other three brain regions 
      commonly implicated in Theory of Mind reasoning--the left temporo-parietal 
      junction (LTPJ), posterior cingulate (PC) and medial prefrontal cortex 
      (MPFC)--showed an equally selective profile of response. The implications of 
      these results for an alternative theory of reasoning about other 
      minds--Simulation Theory--are discussed.
FAU - Saxe, Rebecca
AU  - Saxe R
AD  - Department of Brain and Cognitive Science, MIT, NE20-443, 77 Massachussetts 
      Avenue, Cambridge, MA 02139, USA. saxe@mit.edu
FAU - Wexler, Anna
AU  - Wexler A
LA  - eng
GR  - MH66696/MH/NIMH NIH HHS/United States
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Neuropsychologia
JT  - Neuropsychologia
JID - 0020713
SB  - IM
MH  - Analysis of Variance
MH  - *Brain Mapping
MH  - Concept Formation
MH  - Empathy
MH  - Female
MH  - Humans
MH  - *Interpersonal Relations
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Mental Processes/*physiology
MH  - Parietal Lobe/*physiology
MH  - *Psychological Theory
MH  - Reference Values
MH  - Social Perception
MH  - Temporal Lobe/*physiology
EDAT- 2005/06/07 09:00
MHDA- 2005/11/16 09:00
CRDT- 2005/06/07 09:00
PHST- 2004/07/30 00:00 [received]
PHST- 2005/01/21 00:00 [revised]
PHST- 2005/02/28 00:00 [accepted]
PHST- 2005/06/07 09:00 [pubmed]
PHST- 2005/11/16 09:00 [medline]
PHST- 2005/06/07 09:00 [entrez]
AID - S0028-3932(05)00122-3 [pii]
AID - 10.1016/j.neuropsychologia.2005.02.013 [doi]
PST - ppublish
SO  - Neuropsychologia. 2005;43(10):1391-9. doi: 
      10.1016/j.neuropsychologia.2005.02.013.