PMID- 15946410 OWN - NLM STAT- MEDLINE DCOM- 20050808 LR - 20190719 IS - 0007-1145 (Print) IS - 0007-1145 (Linking) VI - 93 IP - 4 DP - 2005 Apr TI - High rates of exogenous carbohydrate oxidation from a mixture of glucose and fructose ingested during prolonged cycling exercise. PG - 485-92 AB - A recent study from our laboratory has shown that a mixture of glucose and fructose ingested at a rate of 1.8 g/min leads to peak oxidation rates of approximately 1.3 g/min and results in approximately 55% higher exogenous carbohydrate (CHO) oxidation rates compared with the ingestion of an isocaloric amount of glucose. The aim of the present study was to investigate whether a mixture of glucose and fructose when ingested at a high rate (2.4 g/min) would lead to even higher exogenous CHO oxidation rates (>1.3 g/min). Eight trained male cyclists (VO2max: 68+/-1 ml/kg per min) cycled on three different occasions for 150 min at 50% of maximal power output (60+/-1% VO2max) and consumed either water (WAT) or a CHO solution providing 1.2 g/min glucose (GLU) or 1.2 g/min glucose+1.2 g/min fructose (GLU+FRUC). Peak exogenous CHO oxidation rates were higher (P<0.01) in the GLU+FRUC trial compared with the GLU trial (1.75 (SE 0.11) and 1.06 (SE 0.05) g/min, respectively). Furthermore, exogenous CHO oxidation rates during the last 90 min of exercise were approximately 50% higher (P<0.05) in GLU+FRUC compared with GLU (1.49 (SE 0.08) and 0.99 (SE 0.06) g/min, respectively). The results demonstrate that when a mixture of glucose and fructose is ingested at high rates (2.4 g/min) during 150 min of cycling exercise, exogenous CHO oxidation rates reach peak values of approximately 1.75 g/min. FAU - Jentjens, Roy L P G AU - Jentjens RL AD - Human Performance Laboratory, School of Sport and Exercise Sciences, University of Birmingham, Edgbaston B15 2TT, UK. FAU - Jeukendrup, Asker E AU - Jeukendrup AE LA - eng PT - Clinical Trial PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PL - England TA - Br J Nutr JT - The British journal of nutrition JID - 0372547 RN - 0 (Dietary Carbohydrates) RN - 30237-26-4 (Fructose) RN - IY9XDZ35W2 (Glucose) SB - IM MH - Adult MH - Analysis of Variance MH - *Bicycling MH - Dietary Carbohydrates/*administration & dosage/*metabolism MH - Fructose/administration & dosage/metabolism MH - Glucose/administration & dosage/metabolism MH - Humans MH - Isotope Labeling MH - Male MH - Oxidation-Reduction MH - Oxygen Consumption MH - *Physical Endurance EDAT- 2005/06/11 09:00 MHDA- 2005/08/09 09:00 CRDT- 2005/06/11 09:00 PHST- 2005/06/11 09:00 [pubmed] PHST- 2005/08/09 09:00 [medline] PHST- 2005/06/11 09:00 [entrez] AID - S0007114505000619 [pii] AID - 10.1079/bjn20041368 [doi] PST - ppublish SO - Br J Nutr. 2005 Apr;93(4):485-92. doi: 10.1079/bjn20041368.