PMID- 15953437
OWN - NLM
STAT- MEDLINE
DCOM- 20050728
LR  - 20140729
IS  - 0002-9394 (Print)
IS  - 0002-9394 (Linking)
VI  - 139
IP  - 6
DP  - 2005 Jun
TI  - The rate of visual field loss in optic nerve head drusen.
PG  - 1062-6
AB  - PURPOSE: To define the rate of visual field loss in patients with optic nerve 
      head drusen (ONHD). DESIGN: Retrospective chart review. METHODS: Goldmann visual 
      field (GVF) testing from initial visit and last follow-up examination were 
      quantified using the modified Esterman grid technique. The rate of visual field 
      loss was calculated by comparing the initial GVF to the last follow-up GVF. A 
      comparative analysis of GVF and age at initial evaluation was performed on all 
      patients with an initial GVF only. SETTING: Tertiary academic care center. 
      PARTICIPANTS: Inclusion criteria for the rate analysis: (1) diagnosis of ONHD and 
      (2) at least 36 months of follow-up with serial GVF testing. EXCLUSION CRITERIA: 
      (1) patients with glaucoma or glaucoma-suspect; (2) history or examination 
      evidence for other ocular disease; and (3) drusen-related macular causes of 
      visual loss. RESULTS: Thirty-two of 292 charts were included in the rate 
      analysis. The rate of visual field loss was 1.58%. There was no statistically 
      significant difference between men and women (P = .74). One hundred eighty 
      patients were included in the initial visual field analysis. There was a 
      significant negative correlation between age and GVF, with older patients having 
      lower GVF scores with a Spearman correlation of -0.42 (P < 0.0001); 73% of these 
      180 patients had mild, minimal, or no visual field loss. CONCLUSIONS: The rate of 
      visual field loss for ONHD over a 36-month interval of time was 1.6% per year. 
      Patients with minimal or no visual field loss were younger, and patients with 
      moderate or severe visual loss were older.
FAU - Lee, Andrew G
AU  - Lee AG
AD  - Departments of Ophthalmology, Neurology, and Neurosurgery, the University of Iowa 
      Hospitals and Clinics, 200 Hawkins Drive PFP, Iowa City, IA 52242, USA. 
      andrew-lee@uiowa.edu
FAU - Zimmerman, M Bridget
AU  - Zimmerman MB
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Am J Ophthalmol
JT  - American journal of ophthalmology
JID - 0370500
SB  - IM
MH  - Adult
MH  - Female
MH  - Fluorescein Angiography
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Optic Disk/*physiopathology
MH  - Optic Disk Drusen/diagnosis/*physiopathology
MH  - Retrospective Studies
MH  - Tomography, X-Ray Computed
MH  - Vision Disorders/*physiopathology
MH  - Visual Acuity
MH  - *Visual Fields
EDAT- 2005/06/15 09:00
MHDA- 2005/07/29 09:00
CRDT- 2005/06/15 09:00
PHST- 2004/10/15 00:00 [received]
PHST- 2005/01/13 00:00 [revised]
PHST- 2005/01/15 00:00 [accepted]
PHST- 2005/06/15 09:00 [pubmed]
PHST- 2005/07/29 09:00 [medline]
PHST- 2005/06/15 09:00 [entrez]
AID - S0002-9394(05)00089-9 [pii]
AID - 10.1016/j.ajo.2005.01.020 [doi]
PST - ppublish
SO  - Am J Ophthalmol. 2005 Jun;139(6):1062-6. doi: 10.1016/j.ajo.2005.01.020.