PMID- 15964943
OWN - NLM
STAT- MEDLINE
DCOM- 20060410
LR  - 20181113
IS  - 1468-201X (Electronic)
IS  - 1355-6037 (Print)
IS  - 1355-6037 (Linking)
VI  - 92
IP  - 3
DP  - 2006 Mar
TI  - Compliance with and effectiveness of adaptive servoventilation versus continuous 
      positive airway pressure in the treatment of Cheyne-Stokes respiration in heart 
      failure over a six month period.
PG  - 337-42
AB  - OBJECTIVE: To compare compliance with and effectiveness of adaptive 
      servoventilation (ASV) versus continuous positive airway pressure (CPAP) in 
      patients with the central sleep apnoea syndrome (CSA) with Cheyne-Stokes 
      respiration (CSR) and with congestive heart failure in terms of the 
      apnoea-hypopnoea index (AHI), quality of life, and left ventricular ejection 
      fraction (LVEF) over six months. METHODS: 25 patients (age 28-80 years, New York 
      Heart Association (NYHA) class II-IV) with stable congestive heart failure and 
      CSA-CSR were randomly assigned to either CPAP or ASV. At inclusion, both groups 
      were comparable for NYHA class, LVEF, medical treatment, body mass index, and 
      CSA-CSR. RESULTS: Both ASV and CPAP decreased the AHI but, noticeably, only ASV 
      completely corrected CSA-CSR, with AHI below 10/h. At three months, compliance 
      was comparable between ASV and CPAP; however, at six months compliance with CPAP 
      was significantly less than with ASV. At six months, the improvement in quality 
      of life was higher with ASV and only ASV induced a significant increase in LVEF. 
      CONCLUSION: These results suggest that patients with CSA-CSR may receive greater 
      benefit from treatment with ASV than with CPAP.
FAU - Philippe, C
AU  - Philippe C
AD  - Service de Physiologie-Explorations Fonctionnelles, Hopital Tenon, AP-HP, Paris, 
      France.
FAU - Stoica-Herman, M
AU  - Stoica-Herman M
FAU - Drouot, X
AU  - Drouot X
FAU - Raffestin, B
AU  - Raffestin B
FAU - Escourrou, P
AU  - Escourrou P
FAU - Hittinger, L
AU  - Hittinger L
FAU - Michel, P-L
AU  - Michel PL
FAU - Rouault, S
AU  - Rouault S
FAU - d'Ortho, M-P
AU  - d'Ortho MP
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20050617
PL  - England
TA  - Heart
JT  - Heart (British Cardiac Society)
JID - 9602087
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cheyne-Stokes Respiration/complications/*therapy
MH  - Continuous Positive Airway Pressure/methods
MH  - Female
MH  - Heart Failure/*complications
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Compliance
MH  - Quality of Life
MH  - Respiration, Artificial/*methods
MH  - Treatment Outcome
PMC - PMC1860836
COIS- Competing interests: the study was supported by non-profit organisation funds 
      (ADEP Assistance) and a non-commercial donation made by ResMed France to support 
      research in the Creteil Sleep Laboratory in 2001. CP and M-P d'O were reimbursed 
      by ResMed for travel expenses to attend the American Thoracic Society Annual 
      Conference 2004; SR is employed by ADEP Assistance, which is a non-profit 
      organisation for home care. Other authors have no declared conflict of interest.
EDAT- 2005/06/21 09:00
MHDA- 2006/04/11 09:00
PMCR- 2009/03/01
CRDT- 2005/06/21 09:00
PHST- 2005/06/21 09:00 [pubmed]
PHST- 2006/04/11 09:00 [medline]
PHST- 2005/06/21 09:00 [entrez]
PHST- 2009/03/01 00:00 [pmc-release]
AID - hrt.2005.060038 [pii]
AID - ht60038 [pii]
AID - 10.1136/hrt.2005.060038 [doi]
PST - ppublish
SO  - Heart. 2006 Mar;92(3):337-42. doi: 10.1136/hrt.2005.060038. Epub 2005 Jun 17.