PMID- 15972836
OWN - NLM
STAT- MEDLINE
DCOM- 20051011
LR  - 20061115
IS  - 0022-3077 (Print)
IS  - 0022-3077 (Linking)
VI  - 94
IP  - 3
DP  - 2005 Sep
TI  - Similarity of direction tuning among responses to stimulation of different 
      whiskers in neurons of rat barrel cortex.
PG  - 2004-18
AB  - Cells in the rat barrel cortex exhibit stimulus-specific response properties. To 
      understand the network mechanism of direction selectivity in response to facial 
      whisker deflection, we examined direction selectivity of neuronal responses to 
      single- and multi-whisker stimulations. In the case of regular-spiking units, 
      i.e., putative excitatory cells, direction preferences were quite similar between 
      responses to single-whisker stimulation of the principal and adjacent whiskers. 
      In multi-whisker stimulation at short (< or = 5 ms) interstimulus intervals 
      (ISIs), response facilitation was evoked only when the whiskers were deflected to 
      the preferred direction of the response to the single whisker stimulation. These 
      results suggest that there are neuronal networks among cells with different 
      whisker preferences but with a common direction preference that could be the 
      neuronal basis of the direction-selective facilitation of the response to 
      multi-whisker stimulation. In contrast, multi-whisker stimulation at long (> or = 
      6 ms) ISIs caused non-direction-selective suppression of the response to the 
      second stimulus. In the case of fast-spiking units, i.e., putative inhibitory 
      cells, poor direction selectivity was exhibited. Thus stimulus direction is 
      represented as the direction-selective responses to the single- and multi-whisker 
      stimulations of putative excitatory cells rather than those of putative 
      inhibitory cells.
FAU - Kida, Hiroyuki
AU  - Kida H
AD  - Laboratory of Cognitive and Behavioral Neuroscience, Graduate School of Medicine, 
      Osaka University, Machikaneyama 1-17, Toyonaka, Osaka 560-0043, Japan.
FAU - Shimegi, Satoshi
AU  - Shimegi S
FAU - Sato, Hiromichi
AU  - Sato H
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20050622
PL  - United States
TA  - J Neurophysiol
JT  - Journal of neurophysiology
JID - 0375404
SB  - IM
MH  - Action Potentials/physiology
MH  - Afferent Pathways/physiology
MH  - Animals
MH  - Neural Inhibition/*physiology
MH  - Neurons/classification/*physiology
MH  - Orientation/*physiology
MH  - Physical Stimulation/methods
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Reaction Time/physiology/radiation effects
MH  - Regression Analysis
MH  - Somatosensory Cortex/*cytology
MH  - Time Factors
MH  - Vibrissae/innervation/*physiology
EDAT- 2005/06/24 09:00
MHDA- 2005/10/12 09:00
CRDT- 2005/06/24 09:00
PHST- 2005/06/24 09:00 [pubmed]
PHST- 2005/10/12 09:00 [medline]
PHST- 2005/06/24 09:00 [entrez]
AID - 00113.2004 [pii]
AID - 10.1152/jn.00113.2004 [doi]
PST - ppublish
SO  - J Neurophysiol. 2005 Sep;94(3):2004-18. doi: 10.1152/jn.00113.2004. Epub 2005 Jun 
      22.