PMID- 15978345
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20050908
LR  - 20050627
IS  - 0379-0738 (Print)
IS  - 0379-0738 (Linking)
VI  - 152
IP  - 2-3
DP  - 2005 Sep 10
TI  - Rapid and simple method for direct determination of several amphetamines in 
      seized tablets by GC--FID.
PG  - 199-203
AB  - A simple and rapid method for direct simultaneous determination of amphetamine, 
      methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 
      3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxy-N-ethylamphetamine 
      (MDEA) and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB) in seized 
      tablets was developed using gas chromatography with flame ionization detection. 
      Separation of all six underivatized amphetamines, including diphenylamine as 
      internal standard, was performed in about 6 min, using SPB-50 capillary column. 
      Amphetamine and methamphetamine eluted with negligible tailing while the other 
      amphetamines had highly symmetrical peaks. Sensitivity per component on-column 
      was in the nanogram range, and reproducibility from 2.6 to 6.6% at low 
      concentration (2.4 microg/mL) and from 1.2 to 2.6% at high (70 microg/mL) 
      concentration. The method has a wide linear range, from Limit of detection (LOD) 
      to almost 200 microg/mL, thus allowing analysis of different samples across a 
      wide range of possible concentrations of amphetamines. This simple, fast and 
      precise method using gas chromatography--flame ionization detector (GC--FID), in 
      conjunction with other methods (TLC, IR, HPLC), can be used for identification of 
      amphetamines and direct determination in seized tablets, especially in 
      laboratories with heavy workload.
FAU - Mitrevski, Blagoj
AU  - Mitrevski B
AD  - Forensic Science Unit, Ministry of Internal Affairs, Dimce Mircev bb, Skopje 
      1000, Macedonia. blagoj_mitrevski@moi.gov.mk
FAU - Zdravkovski, Zoran
AU  - Zdravkovski Z
LA  - eng
PT  - Journal Article
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
EDAT- 2005/06/28 09:00
MHDA- 2005/06/28 09:01
CRDT- 2005/06/28 09:00
PHST- 2004/05/03 00:00 [received]
PHST- 2004/08/12 00:00 [revised]
PHST- 2004/08/14 00:00 [accepted]
PHST- 2005/06/28 09:00 [pubmed]
PHST- 2005/06/28 09:01 [medline]
PHST- 2005/06/28 09:00 [entrez]
AID - S0379-0738(04)00466-9 [pii]
AID - 10.1016/j.forsciint.2004.08.010 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2005 Sep 10;152(2-3):199-203. doi: 
      10.1016/j.forsciint.2004.08.010.