PMID- 15979718
OWN - NLM
STAT- MEDLINE
DCOM- 20061122
LR  - 20081121
IS  - 0160-4120 (Print)
IS  - 0160-4120 (Linking)
VI  - 32
IP  - 1
DP  - 2006 Jan
TI  - Polychlorinated diphenyl ethers (PCDEs): environmental levels, toxicity and human 
      exposure: a review of the published literature.
PG  - 121-7
AB  - This paper reviews the state of the science regarding polychlorinated diphenyl 
      ethers (PCDEs), a group of halogenated aromatic compounds, which are structurally 
      related to polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans 
      (PCDFs). Special attention is paid to the environmental levels, toxicity, and 
      human exposure. PCDEs have been detected in a number of environmental samples, 
      and their widespread occurrence in the environment is mainly the result of their 
      presence as impurities in chlorophenol preparations. In humans, PCDE congeners 
      have been detected in adipose tissue. As for other persistent organic pollutants 
      (POPs), dietary intake is very probably the main route of exposure to PCDEs for 
      the general population. However, data concerning PCDE levels in foodstuffs are 
      very limited. It is concluded that investigations on experimental toxicity, 
      dietary intake, and potential human health effects of PCDEs are clearly 
      necessary.
FAU - Domingo, Jose L
AU  - Domingo JL
AD  - Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i 
      Virgili University, Reus, Spain. joseluis.domingo@urv.net
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20050624
PL  - Netherlands
TA  - Environ Int
JT  - Environment international
JID - 7807270
RN  - 0 (Environmental Pollutants)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Phenyl Ethers)
RN  - 0 (polychlorinated diphenyl ethers)
SB  - IM
MH  - Animals
MH  - Environmental Exposure/*statistics & numerical data
MH  - Environmental Pollutants/administration & dosage/*analysis/chemistry/*toxicity
MH  - Halogenated Diphenyl Ethers
MH  - Humans
MH  - Phenyl Ethers/administration & dosage/*analysis/chemistry/*toxicity
RF  - 51
EDAT- 2005/06/28 09:00
MHDA- 2006/12/09 09:00
CRDT- 2005/06/28 09:00
PHST- 2005/03/15 00:00 [received]
PHST- 2005/05/16 00:00 [accepted]
PHST- 2005/06/28 09:00 [pubmed]
PHST- 2006/12/09 09:00 [medline]
PHST- 2005/06/28 09:00 [entrez]
AID - S0160-4120(05)00091-7 [pii]
AID - 10.1016/j.envint.2005.05.021 [doi]
PST - ppublish
SO  - Environ Int. 2006 Jan;32(1):121-7. doi: 10.1016/j.envint.2005.05.021. Epub 2005 
      Jun 24.