PMID- 15998196
OWN - NLM
STAT- MEDLINE
DCOM- 20051011
LR  - 20191210
IS  - 0735-7044 (Print)
IS  - 0735-7044 (Linking)
VI  - 119
IP  - 3
DP  - 2005 Jun
TI  - Intracerebroventricular self-administration of commonly abused 
      anabolic-androgenic steroids in male hamsters (Mesocricetus auratus): nandrolone, 
      drostanolone, oxymetholone, and stanozolol.
PG  - 752-8
AB  - Previous studies by the authors have shown voluntary intracerebroventricular 
      (icv) testosterone self-administration in hamsters (Mesocricetus auratus). Here, 
      the authors compared icv self-administration of 4 anabolic steroids 
      (drostanolone, nandrolone, oxymetholone, and stanozolol) at 0.1, 1.0, and 2.0 
      microg/microl, each for 8 days. Males (n=8/group) showed the highest levels of 
      operant behavior for injectable steroids (drostanolone, nandrolone) compared with 
      orally active androgens (oxymetholone, stanozolol). For nandrolone, responses on 
      the active and inactive nose-pokes averaged 22.3 +/- 4.6/4 hr and 10.7 +/- 2.0/4 
      hr, respectively. Responding for drostanolone was similar. Males 
      self-administering oxymetholone or stanozolol did not prefer the active 
      nose-poke. These data demonstrate that injectable androgens are more reinforcing 
      than oral steroids.
CI  - (c) 2005 APA, all rights reserved.
FAU - Ballard, Cortney L
AU  - Ballard CL
AD  - Department of Cell and Neurobiology, Keck School of Medicine, University of 
      Southern California, Los Angeles, CA 90033, USA.
FAU - Wood, Ruth I
AU  - Wood RI
LA  - eng
GR  - DA-12843/DA/NIDA NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Behav Neurosci
JT  - Behavioral neuroscience
JID - 8302411
RN  - 0 (Androgens)
RN  - 0 (Androstanols)
RN  - 4R1VB9P8V3 (Stanozolol)
RN  - 6PG9VR430D (Nandrolone)
RN  - 7DR7H00HDT (dromostanolone)
RN  - L76T0ZCA8K (Oxymetholone)
SB  - IM
MH  - Analysis of Variance
MH  - Androgens/*administration & dosage
MH  - Androstanols/administration & dosage
MH  - Animals
MH  - Behavior, Animal/drug effects
MH  - Conditioning, Operant/*drug effects
MH  - Cricetinae
MH  - Dose-Response Relationship, Drug
MH  - Drug Administration Routes
MH  - Exploratory Behavior/drug effects
MH  - Injections, Intraventricular
MH  - Male
MH  - Nandrolone/administration & dosage
MH  - Oxymetholone/administration & dosage
MH  - *Reinforcement, Psychology
MH  - Self Administration/methods
MH  - Stanozolol/administration & dosage
MH  - Substance-Related Disorders/*physiopathology
MH  - Time Factors
EDAT- 2005/07/07 09:00
MHDA- 2005/10/12 09:00
CRDT- 2005/07/07 09:00
PHST- 2005/07/07 09:00 [pubmed]
PHST- 2005/10/12 09:00 [medline]
PHST- 2005/07/07 09:00 [entrez]
AID - 2005-06959-012 [pii]
AID - 10.1037/0735-7044.119.3.752 [doi]
PST - ppublish
SO  - Behav Neurosci. 2005 Jun;119(3):752-8. doi: 10.1037/0735-7044.119.3.752.