PMID- 16010169
OWN - NLM
STAT- MEDLINE
DCOM- 20050914
LR  - 20200930
IS  - 1525-4135 (Print)
IS  - 1525-4135 (Linking)
VI  - 39
IP  - 4
DP  - 2005 Aug 1
TI  - Is sexually transmitted infection management among sex workers still able to 
      mitigate the spread of HIV infection in West Africa?
PG  - 454-8
AB  - OBJECTIVE: To assess the role of sexually transmitted infection (STI) management 
      to prevent HIV acquisition among sex workers in Burkina Faso. DESIGN: Open cohort 
      study of professional and nonprofessional sex workers with 3-month follow-up 
      visits. METHODS: Baseline and follow-up visits consisted of the administration of 
      a behavioral questionnaire, education sessions on HIV and STIs, a medical 
      examination, and laboratory testing for STI and HIV diagnosis. RESULTS: Three 
      hundred seventy-seven HIV-negative women were enrolled in the study. The 
      cumulated HIV incidence was 3.2 per 100 person-years (Poisson 95% confidence 
      interval: 1.9-4.9). Bacterial and parasitic STIs were low at baseline, whereas 
      herpes simplex virus-2 (HSV-2) prevalence was 54.7%. By a Cox regression model, 
      self-assessment of high HIV risk in the past, less than 5 clients per week, and 
      no change of a steady partner were independently associated with HIV acquisition. 
      Among STIs, only infection with HSV-2 tended to be associated with HIV 
      acquisition (odds ratio = 2.45; P = 0.15). Overall, condom use increased during 
      the study but to a lesser extent with steady partners. CONCLUSIONS: Bacterial and 
      parasitic STIs are no longer a key determinant of HIV acquisition, given the 
      current stage of the outbreak in Burkina Faso. Although efforts for STI control 
      should be maintained, strategies should focus on nonprofessional sex workers, 
      steady partners, and HSV-2 infection to tackle HIV transmission further in this 
      high-risk group.
FAU - Nagot, Nicolas
AU  - Nagot N
AD  - From the Centre Muraz, Bobo-Dioulasso, Burkina Faso.
FAU - Ouedraogo, Abdoulaye
AU  - Ouedraogo A
FAU - Ouangre, Amadou
AU  - Ouangre A
FAU - Cartoux, Michel
AU  - Cartoux M
FAU - Defer, Marie-Christine
AU  - Defer MC
FAU - Meda, Nicolas
AU  - Meda N
FAU - Van de Perre, Philippe
AU  - Van de Perre P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Acquir Immune Defic Syndr
JT  - Journal of acquired immune deficiency syndromes (1999)
JID - 100892005
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Burkina Faso/epidemiology
MH  - Cohort Studies
MH  - Community Health Services
MH  - Condoms
MH  - Female
MH  - HIV Infections/epidemiology/prevention & control/*transmission
MH  - Humans
MH  - Incidence
MH  - Parasitic Diseases/epidemiology/transmission
MH  - Risk Factors
MH  - *Sex Work
MH  - Sexually Transmitted Diseases/*epidemiology/*prevention & control
MH  - Sexually Transmitted Diseases, Bacterial/epidemiology
EDAT- 2005/07/13 09:00
MHDA- 2005/09/15 09:00
CRDT- 2005/07/13 09:00
PHST- 2005/07/13 09:00 [pubmed]
PHST- 2005/09/15 09:00 [medline]
PHST- 2005/07/13 09:00 [entrez]
AID - 00126334-200508010-00014 [pii]
AID - 10.1097/01.qai.0000152399.54648.b9 [doi]
PST - ppublish
SO  - J Acquir Immune Defic Syndr. 2005 Aug 1;39(4):454-8. doi: 
      10.1097/01.qai.0000152399.54648.b9.