PMID- 16013230
OWN - NLM
STAT- MEDLINE
DCOM- 20150516
LR  - 20181201
IS  - 1001-5515 (Print)
IS  - 1001-5515 (Linking)
VI  - 22
IP  - 3
DP  - 2005 Jun
TI  - [Synthesis of a bio-active bone-matrix material and study of the cellular 
      biocompatibility].
PG  - 433-7
AB  - To prepare poly(lactic acid/glycolic acid/ asparagic acid-co- polyethylene 
      glycol) (PLGA-[ASP-PEG]) and examine the cellular biocompatibility. 
      PLGA-[ASP-PEG] was obtained by bulk ring-opening copolymerization method, 
      examined by infrared spectrometry (IR) and 1H nuclear magnetic resonance 
      spectroscopy (1H NMR). Bone marrow stromal cells(BMSCs) were cultured with 
      PLGA-[ASP-PEG] (experiment gruop) and PLGA (control group) in vitro respectively, 
      and were observed by phase-contrast microscopy and scanning electron microscopy. 
      The resuls showed that PLGA-[ASP-PEG] was obtained and proved by IR and 1H NMR. 
      The BMSCs of the experiment group could well attach to and extend on the surface 
      of the PLGA-[ASP-PEG], and could proliferate and secrete better extracellular 
      matrix, compared with control. The PLGA-[ASP-PEG] has good cellular a 
      biocompatibility. It can be used as a biomaterial for bone tissue engineering.
FAU - Hao, Jie
AU  - Hao J
AD  - Department of Orthopedics, Union Hospital, Tongji Medical College of Huazhong 
      Science and Technology University, Wuhan 430022, China. hjie2005@yahoo.com.cn
FAU - Zheng, Qixin
AU  - Zheng Q
FAU - Guo, Xiaodong
AU  - Guo X
FAU - Quan, Daping
AU  - Quan D
FAU - Luo, Binghong
AU  - Luo B
LA  - chi
PT  - Journal Article
PL  - China
TA  - Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
JT  - Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = 
      Shengwu yixue gongchengxue zazhi
JID - 9426398
RN  - 0 (Biocompatible Materials)
RN  - 0 (Polyesters)
RN  - 0 (Polymers)
RN  - 1SIA8062RS (Polylactic Acid-Polyglycolic Acid Copolymer)
RN  - 26009-03-0 (Polyglycolic Acid)
RN  - 30KYC7MIAI (Aspartic Acid)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 3WJQ0SDW1A (Polyethylene Glycols)
RN  - 459TN2L5F5 (poly(lactide))
SB  - IM
MH  - Aspartic Acid/chemistry
MH  - *Biocompatible Materials
MH  - Bone Matrix/*cytology
MH  - Lactic Acid/*chemistry
MH  - Mesenchymal Stem Cells/cytology
MH  - Polyesters
MH  - Polyethylene Glycols/*chemistry
MH  - Polyglycolic Acid/chemistry
MH  - Polylactic Acid-Polyglycolic Acid Copolymer
MH  - Polymers/*chemistry
MH  - Tissue Engineering
EDAT- 2005/07/15 09:00
MHDA- 2015/05/20 06:00
CRDT- 2005/07/15 09:00
PHST- 2005/07/15 09:00 [pubmed]
PHST- 2015/05/20 06:00 [medline]
PHST- 2005/07/15 09:00 [entrez]
PST - ppublish
SO  - Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2005 Jun;22(3):433-7.