PMID- 16030286
OWN - NLM
STAT- MEDLINE
DCOM- 20060420
LR  - 20221103
IS  - 1525-8882 (Electronic)
IS  - 1525-8882 (Linking)
VI  - 2005
IP  - 293
DP  - 2005 Jul 19
TI  - Interleukin-13 (IL-13) pathway.
PG  - cm8
AB  - Interleukin-13 (IL-13), like IL-4, is a cytokine produced by T(H)2 type helper T 
      cells in response to signaling through the T cell antigen receptor and by mast 
      cells and basophils upon cross-linkage of the high-affinity receptor for 
      immunoglobulin E (IgE). It is also produced by activated eosinophils. IL-13 
      induces many of the same responses as IL-4 and shares a receptor subunit with 
      IL-4. IL-13 has been implicated in airway hypersensitivity and mucus 
      hypersecretion, inflammatory bowel disease, and parasitic nematode expulsion.
FAU - Kelly-Welch, Ann
AU  - Kelly-Welch A
AD  - Program in Oncology, Marlene and Stewart Greenebaum Cancer Center and Department 
      of Microbiology and Immunology, University of Maryland, Baltimore, USA.
FAU - Hanson, Erica M
AU  - Hanson EM
FAU - Keegan, Achsah D
AU  - Keegan AD
LA  - eng
PT  - Journal Article
DEP - 20050719
PL  - United States
TA  - Sci STKE
JT  - Science's STKE : signal transduction knowledge environment
JID - 100964423
RN  - 0 (IL13RA1 protein, human)
RN  - 0 (Interleukin-13)
RN  - 0 (Interleukin-13 Receptor alpha1 Subunit)
RN  - 0 (Receptors, Interleukin)
RN  - 0 (Receptors, Interleukin-13)
RN  - 0 (Receptors, Interleukin-4)
RN  - EC 2.7.10.1 (Protein-Tyrosine Kinases)
SB  - IM
MH  - Animals
MH  - Dimerization
MH  - Humans
MH  - Interleukin-13/pharmacology/*physiology
MH  - Interleukin-13 Receptor alpha1 Subunit
MH  - *Models, Biological
MH  - Protein-Tyrosine Kinases/physiology
MH  - Receptors, Interleukin/chemistry/drug effects/physiology
MH  - Receptors, Interleukin-13
MH  - Receptors, Interleukin-4/chemistry/physiology
MH  - Signal Transduction/drug effects/*physiology
EDAT- 2005/07/21 09:00
MHDA- 2006/04/21 09:00
CRDT- 2005/07/21 09:00
PHST- 2005/07/21 09:00 [pubmed]
PHST- 2006/04/21 09:00 [medline]
PHST- 2005/07/21 09:00 [entrez]
AID - stke.2932005cm8 [pii]
AID - 10.1126/stke.2932005cm8 [doi]
PST - epublish
SO  - Sci STKE. 2005 Jul 19;2005(293):cm8. doi: 10.1126/stke.2932005cm8.