PMID- 16030474 OWN - NLM STAT- MEDLINE DCOM- 20051007 LR - 20050720 IS - 1341-1098 (Print) IS - 1341-1098 (Linking) VI - 11 IP - 3 DP - 2005 Jun TI - Late development of mitral regurgitation after left ventricular reconstruction surgery. PG - 159-63 AB - PURPOSE: Late presence of mitral regurgitation (MR) after the Dor procedure (left ventricular (LV) reconstruction associated with coronary artery bypass grafting) for postinfarction patients carries a poor prognosis. The aim of this study was to review our experience with the Dor procedure and to analyze the correlation of surgical results with late MR. METHODS: The study group comprised 19 patients with previous anterior transmural myocardial infarction (MI). Ten patients were classified as New York Heart Association (NYHA) functional class III or IV at surgery. MR was moderate in 2 patients and mild in 15 patients. RESULTS: Myocardial revascularization was performed in all patients, with a mean of 3.7+/-1.2 grafts. Mitral valve was repaired in 6 patients. Four patients with mild MR underwent posterior annuloplasty, and 2 with moderate MR underwent rigid annular remodeling. Early postoperative NYHA functional class improved from 2.7+/-0.9 to 1.3+/-0.5; however, MR deteriorated to moderate in 5 patients with worsening NYHA functional class 3 months after surgery. Although the valve was not repaired during surgery in 4 patients with preoperative mild MR, 1 patient with moderate MR underwent annuloplasty with a rigid ring. All patients with late MR underwent more than 30-mL/m2 reduction of end-diastolic volume index at surgery. Cumulative 4-year survival including hospital deaths was 89.5%. CONCLUSION: To prevent the risk of late MR, a more than 30-mL/m2 reduction of end-diastolic volume index should be avoided and mitral valve repair should be performed even if preoperative functional MR is only mild. FAU - Yotsumoto, Goichi AU - Yotsumoto G AD - Second Department of Surgery, Kagoshima University, Kagoshima, Japan. FAU - Sakata, Ryuzo AU - Sakata R FAU - Ueno, Takayuki AU - Ueno T FAU - Iguro, Yoshifumi AU - Iguro Y FAU - Kinjo, Tamahiro AU - Kinjo T FAU - Kobayashi, Akira AU - Kobayashi A FAU - Matsumoto, Kazuhisa AU - Matsumoto K FAU - Tei, Chuwa AU - Tei C FAU - Otsuji, Yutaka AU - Otsuji Y FAU - Tanaka, Yasuhiro AU - Tanaka Y LA - eng PT - Journal Article PL - Japan TA - Ann Thorac Cardiovasc Surg JT - Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia JID - 9703158 SB - IM MH - Aged MH - Cardiopulmonary Bypass MH - Female MH - Heart Ventricles/*surgery MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve Insufficiency/*etiology MH - Myocardial Infarction/*surgery MH - Retrospective Studies MH - Ventricular Dysfunction, Left/*surgery EDAT- 2005/07/21 09:00 MHDA- 2005/10/08 09:00 CRDT- 2005/07/21 09:00 PHST- 2005/07/21 09:00 [pubmed] PHST- 2005/10/08 09:00 [medline] PHST- 2005/07/21 09:00 [entrez] PST - ppublish SO - Ann Thorac Cardiovasc Surg. 2005 Jun;11(3):159-63.