PMID- 16035389 OWN - NLM STAT- MEDLINE DCOM- 20051215 LR - 20191109 IS - 0043-5341 (Print) IS - 0043-5341 (Linking) VI - 155 IP - 11-12 DP - 2005 Jun TI - [Tumor cytogenetics]. PG - 281-8 AB - Cytogenetic analysis by classical chromosome banding, in combination with different fluorescence in situ hybridization (FISH) based methods, including comparative genomic hybridization and multicolour FISH, provides important information concerning the diagnosis, staging and prognosis of, as well as the planning of therapeutic intervention against, leukemias, malignant lymphomas and solid tumors, and may be helpful in monitoring the course of the disease. Cytogenetic methods identify primary chromosome anomalies that are causally involved in the emergence of the disease and its histopathological subtype, as well as secondary anomalies which have an effect upon the course of the disease and the responsiveness to therapy. Tumor cytogenetics is an independent discipline, and by no means only a diagnostic service for, or subdiscipline of, haematological, oncological and pathological fields. It is important, however, to point out that tumor cytogenetics is a cooperation-orientated and interdisciplinary science that deals with its own original questions in collaboration with clinicians, pathologists and molecular geneticists. FAU - Fonatsch, Christa AU - Fonatsch C AD - Abteilung fur Humangenetik, Klinisches Institut fur Medizinische und Chemische Labordiagnostik, Medizinische Universitat Wien, Wien, Osterreich. christa.fonatsch@meduniwien.ac.at FAU - Kromer, Elisabeth AU - Kromer E LA - ger PT - English Abstract PT - Journal Article TT - Tumorzytogenetik. PL - Austria TA - Wien Med Wochenschr JT - Wiener medizinische Wochenschrift (1946) JID - 8708475 SB - IM MH - Cell Transformation, Neoplastic/genetics/pathology MH - Chromosome Aberrations MH - Chromosome Banding MH - Cooperative Behavior MH - *Cytogenetic Analysis MH - Humans MH - In Situ Hybridization, Fluorescence MH - Karyotyping MH - Leukemia/diagnosis/*genetics/pathology/therapy MH - Lymphoma/diagnosis/*genetics/pathology/therapy MH - Neoplasm Staging MH - Neoplasms/diagnosis/*genetics/pathology/therapy MH - Patient Care Team MH - Prognosis EDAT- 2005/07/23 09:00 MHDA- 2005/12/16 09:00 CRDT- 2005/07/23 09:00 PHST- 2005/07/23 09:00 [pubmed] PHST- 2005/12/16 09:00 [medline] PHST- 2005/07/23 09:00 [entrez] AID - 10.1007/s10354-005-0186-0 [doi] PST - ppublish SO - Wien Med Wochenschr. 2005 Jun;155(11-12):281-8. doi: 10.1007/s10354-005-0186-0.